Literature DB >> 9628915

Caged RNA: photo-control of a ribozyme reaction.

S G Chaulk1, A M MacMillan.   

Abstract

We report here the first photo-chemical control of a ribozyme reaction by the site-specific modification of the 2'-hydroxyl nucleophile in the hammerhead system with a caging functionality. Rapid laser photolysis of the O-(2-nitrobenzyl) caging group initiates an efficient and accurate hammerhead-catalyzed cleavage of substrate RNA under native conditions. RNAs in which reactive functionalities or recognition elements are caged in this manner will be useful tools to probe RNA reactivity and dynamics.

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Year:  1998        PMID： 9628915      PMCID： PMC147693          DOI： 10.1093/nar/26.13.3173

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  27 in total

1.  The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage.

Authors:  W G Scott; J T Finch; A Klug
Journal:  Cell       Date:  1995-06-30       Impact factor: 41.582

Review 2.  Structure and function of the hammerhead ribozyme: an unfinished story.

Authors:  D B McKay
Journal:  RNA       Date:  1996-05       Impact factor: 4.942

Review 3.  RNA folding.

Authors:  A M Pyle; J B Green
Journal:  Curr Opin Struct Biol       Date:  1995-06       Impact factor: 6.809

4.  Probing RNA tertiary structure: interhelical crosslinking of the hammerhead ribozyme.

Authors:  S T Sigurdsson; T Tuschl; F Eckstein
Journal:  RNA       Date:  1995-08       Impact factor: 4.942

5.  Branch nucleophile selection in pre-mRNA splicing: evidence for the bulged duplex model.

Authors:  C C Query; M J Moore; P A Sharp
Journal:  Genes Dev       Date:  1994-03-01       Impact factor: 11.361

6.  Kinetic intermediates in RNA folding.

Authors:  P P Zarrinkar; J R Williamson
Journal:  Science       Date:  1994-08-12       Impact factor: 47.728

7.  Dynamic association of proteins with the pre-mRNA branch region.

Authors:  A M MacMillan; C C Query; C R Allerson; S Chen; G L Verdine; P A Sharp
Journal:  Genes Dev       Date:  1994-12-15       Impact factor: 11.361

8.  Crystal structure of a group I ribozyme domain: principles of RNA packing.

Authors:  J H Cate; A R Gooding; E Podell; K Zhou; B L Golden; C E Kundrot; T R Cech; J A Doudna
Journal:  Science       Date:  1996-09-20       Impact factor: 47.728

9.  Synthesis, kinetics, and structural studies of a photolabile caged isocitrate: a catalytic trigger for isocitrate dehydrogenase.

Authors:  M J Brubaker; D H Dyer; B Stoddard; D E Koshland
Journal:  Biochemistry       Date:  1996-03-05       Impact factor: 3.162

10.  Efficient trans-cleavage of a stem-loop RNA substrate by a ribozyme derived from neurospora VS RNA.

Authors:  H C Guo; R A Collins
Journal:  EMBO J       Date:  1995-01-16       Impact factor: 11.598
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  27 in total

1.  Combined Approaches to Site-Specific Modification of RNA.

Authors:  Christine S Chow; Santosh K Mahto; Tek N Lamichhane
Journal:  ACS Chem Biol       Date:  2008-01-05       Impact factor: 5.100

2.  Synthesis, properties, and applications of oligonucleotides containing an RNA dinucleotide phosphorothiolate linkage.

Authors:  Nan-Sheng Li; John K Frederiksen; Joseph A Piccirilli
Journal:  Acc Chem Res       Date:  2011-09-01       Impact factor: 22.384

Review 3.  Optochemical Control of Biological Processes in Cells and Animals.

Authors:  Nicholas Ankenbruck; Taylor Courtney; Yuta Naro; Alexander Deiters
Journal:  Angew Chem Int Ed Engl       Date:  2018-02-01       Impact factor: 15.336

4.  Optical Control of Metal Ion Probes in Cells and Zebrafish Using Highly Selective DNAzymes Conjugated to Upconversion Nanoparticles.

Authors:  Zhenglin Yang; Kang Yong Loh; Yueh-Te Chu; Ruopei Feng; Nitya Sai Reddy Satyavolu; Mengyi Xiong; Stephanie M Nakamata Huynh; Kevin Hwang; Lele Li; Hang Xing; Xiaobing Zhang; Yann R Chemla; Martin Gruebele; Yi Lu
Journal:  J Am Chem Soc       Date:  2018-12-04       Impact factor: 15.419

5.  Photocaged DNAzymes as a general method for sensing metal ions in living cells.

Authors:  Kevin Hwang; Peiwen Wu; Taejin Kim; Lei Lei; Shiliang Tian; Yingxiao Wang; Yi Lu
Journal:  Angew Chem Int Ed Engl       Date:  2014-10-14       Impact factor: 15.336

6.  Photoreleasable ligands to study intracrine angiotensin II signalling.

Authors:  Artavazd Tadevosyan; Myriam Létourneau; Benjamin Folch; Nicolas Doucet; Louis R Villeneuve; Aida M Mamarbachi; Darlaine Pétrin; Terence E Hébert; Alain Fournier; David Chatenet; Bruce G Allen; Stanley Nattel
Journal:  J Physiol       Date:  2015-01-07       Impact factor: 5.182

7.  Site-Selective RNA Functionalization via DNA-Induced Structure.

Authors:  Lu Xiao; Maryam Habibian; Eric T Kool
Journal:  J Am Chem Soc       Date:  2020-09-14       Impact factor: 15.419

8.  RNA Cloaking by Reversible Acylation.

Authors:  Anastasia Kadina; Anna M Kietrys; Eric T Kool
Journal:  Angew Chem Int Ed Engl       Date:  2018-02-22       Impact factor: 15.336

9.  RNA bandages for photoregulating in vitro protein synthesis.

Authors:  Julia L Richards; XinJing Tang; Anna Turetsky; Ivan J Dmochowski
Journal:  Bioorg Med Chem Lett       Date:  2008-09-30       Impact factor: 2.823

10.  Light-activated RNA interference using double-stranded siRNA precursors modified using a remarkable regiospecificity of diazo-based photolabile groups.

Authors:  Samit Shah; Piyush K Jain; Ashish Kala; Dipu Karunakaran; Simon H Friedman
Journal:  Nucleic Acids Res       Date:  2009-05-28       Impact factor: 16.971
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