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Literature DB >> 9545191

Population genetics: surviving under mutation pressure.

P D Keightley¹, A Caballero, A García-Dorado.

Abstract

Concern has been voiced about the survival of endangered species, and even the long-term prospects for humans, in the face of accumulating deleterious mutations. Two experiments have investigated the mutation accumulation process in laboratory Drosophila populations, with apparently conflicting results.

Entities: Species

Mesh：

Year: 1998 PMID： 9545191 DOI： 10.1016/s0960-9822(98)70148-4

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

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Cited

12 in total

1. Whole-genome effects of ethyl methanesulfonate-induced mutation on nine quantitative traits in outbred Drosophila melanogaster.

Authors: H P Yang; A Y Tanikawa; W A Van Voorhies; J C Silva; A S Kondrashov
Journal: Genetics Date: 2001-03 Impact factor: 4.562

2. The rate of mutation and the homozygous and heterozygous mutational effects for competitive viability: a long-term experiment with Drosophila melanogaster.

Authors: D Chavarrías; C López-Fanjul; A García-Dorado
Journal: Genetics Date: 2001-06 Impact factor: 4.562

3. Simultaneous Estimation of Additive and Mutational Genetic Variance in an Outbred Population of Drosophila serrata.

Authors: Katrina McGuigan; J David Aguirre; Mark W Blows
Journal: Genetics Date: 2015-09-16 Impact factor: 4.562

4. Relaxation of selection with equalization of parental contributions in conservation programs: an experimental test with Drosophila melanogaster.

Authors: S T Rodríguez-Ramilo; P Morán; A Caballero
Journal: Genetics Date: 2005-11-19 Impact factor: 4.562

Population genetics: surviving under mutation pressure.

1. Whole-genome effects of ethyl methanesulfonate-induced mutation on nine quantitative traits in outbred Drosophila melanogaster.

2. The rate of mutation and the homozygous and heterozygous mutational effects for competitive viability: a long-term experiment with Drosophila melanogaster.

3. Simultaneous Estimation of Additive and Mutational Genetic Variance in an Outbred Population of Drosophila serrata.

4. Relaxation of selection with equalization of parental contributions in conservation programs: an experimental test with Drosophila melanogaster.

5. Cumulative effects of spontaneous mutations for fitness in Caenorhabditis: role of genotype, environment and stress.

6. Breeding designs for recombinant inbred advanced intercross lines.

7. Inference of genome-wide mutation rates and distributions of mutation effects for fitness traits: a simulation study.

8. New estimates of the rates and effects of mildly deleterious mutation in Drosophila melanogaster.

9. Spontaneous mutational effects on reproductive traits of arabidopsis thaliana.

10. Sex is always well worth its two-fold cost.