Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 DNA binding within the nucleosome core.

Literature DB >> 9519294

DNA binding within the nucleosome core.

Abstract

The high resolution structure of the nucleosome core particle of chromatin reveals the form of DNA that is predominant in living cells and offers a wealth of information on DNA binding and bending by the histone octamer. Recent studies imply that chromatin is highly dynamic. This propensity for unfolding and refolding stems from the structural design of the nucleosome core. The histone-fold motif, central to nucleosome structure, is also found in other proteins involved in transcriptional regulation.

Mesh：

Substances：

Year: 1998 PMID： 9519294 DOI： 10.1016/s0959-440x(98)80007-9

Source DB: PubMed Journal: Curr Opin Struct Biol ISSN： 0959-440X Impact factor: 6.809

Keyword Cloud
Cited

93 in total

Review 1. Role of histone acetylation in the assembly and modulation of chromatin structures.

Authors: A T Annunziato; J C Hansen
Journal: Gene Expr Date: 2000

2. Effects of histone tail domains on the rate of transcriptional elongation through a nucleosome.

Authors: R U Protacio; G Li; P T Lowary; J Widom
Journal: Mol Cell Biol Date: 2000-12 Impact factor: 4.272

3. Mechanical disruption of individual nucleosomes reveals a reversible multistage release of DNA.

Authors: Brent D Brower-Toland; Corey L Smith; Richard C Yeh; John T Lis; Craig L Peterson; Michelle D Wang
Journal: Proc Natl Acad Sci U S A Date: 2002-02-19 Impact factor: 11.205

4. DNA repair of a single UV photoproduct in a designed nucleosome.

Authors: J V Kosmoski; E J Ackerman; M J Smerdon
Journal: Proc Natl Acad Sci U S A Date: 2001-08-21 Impact factor: 11.205

Review 5. Optical tweezers stretching of chromatin.

Authors: Lisa H Pope; Martin L Bennink; Jan Greve
Journal: J Muscle Res Cell Motil Date: 2002 Impact factor: 2.698

6. Conserved eukaryotic histone-fold residues substituted into an archaeal histone increase DNA affinity but reduce complex flexibility.

Authors: Divya J Soares; Frédéric Marc; John N Reeve
Journal: J Bacteriol Date: 2003-06 Impact factor: 3.490

DNA binding within the nucleosome core.

Review 1. Role of histone acetylation in the assembly and modulation of chromatin structures.

2. Effects of histone tail domains on the rate of transcriptional elongation through a nucleosome.

3. Mechanical disruption of individual nucleosomes reveals a reversible multistage release of DNA.

4. DNA repair of a single UV photoproduct in a designed nucleosome.

Review 5. Optical tweezers stretching of chromatin.

6. Conserved eukaryotic histone-fold residues substituted into an archaeal histone increase DNA affinity but reduce complex flexibility.

7. Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions.

Review 8. Nucleosome sliding: facts and fiction.

9. A determining influence for CpG dinucleotides on nucleosome positioning in vitro.

Review 10. Role of chromatin states in transcriptional memory.