Literature DB >> 9396815

The methylated DNA binding protein-2-H1 (MDBP-2-H1) consists of histone H1 subtypes which are truncated at the C-terminus.

S Schwarz1, D Hess, J P Jost.   

Abstract

The methylated DNA binding protein-2-H1 (MDBP-2-H1), present in rooster liver, is a member of the histone H1 family which inhibits transcription by binding selectively to methylated promoters. Here we have determined the primary structure of MDBP-2-H1. A comparison between histone H1 and MDBP-2-H1 was achieved by analyzing reversed phase HPLC-purified and V8-digested proteins by mass spectrometry and/or microsequencing. In rooster liver the most abundant histone H1 subtypes are H1 01 and H1 11L. Similarly, MDBP-2-H1 contains the same subtypes of histone H1. The histone H1 subtype H1 01 in MDBP-2-H1 has 150 amino acids, whereas the full-size histone H1 01 is 218 amino acids. The difference in mass between the two proteins is explained by C-terminal truncation of histone H1 01.

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Year:  1997        PMID： 9396815      PMCID： PMC147137          DOI： 10.1093/nar/25.24.5052

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  27 in total

1.  Genomic sequencing reveals a positive correlation between the kinetics of strand-specific DNA demethylation of the overlapping estradiol/glucocorticoid-receptor binding sites and the rate of avian vitellogenin mRNA synthesis.

Authors:  H P Saluz; J Jiricny; J P Jost
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

2.  Transitions in histone variants during sea urchin spermatogenesis.

Authors:  D L Poccia; M V Simpson; G R Green
Journal:  Dev Biol       Date:  1987-06       Impact factor: 3.582

3.  Differences in the binding of H1 variants to DNA. Cooperativity and linker-length related distribution.

Authors:  D J Clark; J O Thomas
Journal:  Eur J Biochem       Date:  1988-12-01

4.  Characterization of the chicken histone H1 gene complement. Generation of a complete set of vertebrate H1 protein sequences.

Authors:  L S Coles; A J Robins; L K Madley; J R Wells
Journal:  J Biol Chem       Date:  1987-07-15       Impact factor: 5.157

5.  Characterization of the six chicken histone H1 proteins and alignment with their respective genes.

Authors:  M F Shannon; J R Wells
Journal:  J Biol Chem       Date:  1987-07-15       Impact factor: 5.157

6.  An H1 histone gene-specific 5' element and evolution of H1 and H5 genes.

Authors:  L S Coles; J R Wells
Journal:  Nucleic Acids Res       Date:  1985-01-25       Impact factor: 16.971

7.  5-methylcytosine is localized in nucleosomes that contain histone H1.

Authors:  D J Ball; D S Gross; W T Garrard
Journal:  Proc Natl Acad Sci U S A       Date:  1983-09       Impact factor: 11.205

8.  An avian 40 KDa nucleoprotein binds preferentially to a promoter sequence containing one single pair of methylated CpG.

Authors:  A Pawlak; M Bryans; J P Jost
Journal:  Nucleic Acids Res       Date:  1991-03-11       Impact factor: 16.971

9.  Genomic sequencing and in vivo footprinting of an expression-specific DNase I-hypersensitive site of avian vitellogenin II promoter reveal a demethylation of a mCpG and a change in specific interactions of proteins with DNA.

Authors:  H P Saluz; I M Feavers; J Jiricny; J P Jost
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

10.  Genomic organization, DNA sequence, and expression of chicken embryonic histone genes.

Authors:  B J Sugarman; J B Dodgson; J D Engel
Journal:  J Biol Chem       Date:  1983-07-25       Impact factor: 5.157
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  1 in total

1.  Glucocorticoid-induced DNA demethylation and gene memory during development.

Authors:  H Thomassin; M Flavin; M L Espinás; T Grange
Journal:  EMBO J       Date:  2001-04-17       Impact factor: 11.598
  1 in total

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