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Literature DB >> 93285

Induction of calcium flux across the rat mast cell membrane by bridging IgE receptors.

T Ishizaka, J C Foreman, A R Sterk, K Ishizaka.

Abstract

Rabbit antibody against IgE receptors or its F(ab')2 fragments induced an increase of 45Ca uptake into normal mast cells, and this process was accompanied by histamine release. Evidence was obtained that a substantial portion of 45Ca uptake was due to movement of calcium across the cell membrane. Neither 45Ca uptake nor histamine release was induced by Fab' monomer fragments of the antireceptor antibody. However, bridging of receptor-bound Fab' fragments by antirabbit IgG or bridging of receptor-bound IgE by anti-IgE induced an increase in 45Ca uptake. The results collectively indicate that crosslinking IgE receptors increases the membrane permeability of the mast cells toward calcium.

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Year: 1979 PMID： 93285 PMCID： PMC411751 DOI： 10.1073/pnas.76.11.5858

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

26 in total

1. REAGIN-LIKE ANTIBODIES IN ANIMALS IMMUNE TO HELMINTH PARASITES.

Authors: B M OGILVIE
Journal: Nature Date: 1964-10-03 Impact factor: 49.962

2. The effect of calcium and pH on the anaphylactic reaction.

Authors: J L MONGAR; H O SCHILD
Journal: J Physiol Date: 1958-02-17 Impact factor: 5.182

3. Triggering of cultured neoplastic mast cells by antibodies to the receptor for IgE.

Authors: C Isersky; J D Taurog; G Poy; H Metzger
Journal: J Immunol Date: 1978-08 Impact factor: 5.422

4. Release of histamine and slow reacting substance of anaphylaxis (SRS-A) by IgE-anti-IgE reactions on monkey mast cells.

Authors: T Ishizaka; K Ishizaka; H Tomioka
Journal: J Immunol Date: 1972-02 Impact factor: 5.422

5. Phosphatidylserine: selective enhancer of histamine release.

Authors: A Goth; H R Adams; M Knoohuizen
Journal: Science Date: 1971-09-10 Impact factor: 47.728

6. Biologic function of the Fc fragments of E myeloma protein.

Authors: K Ishizaka; T Ishizaka; E H Lee
Journal: Immunochemistry Date: 1970-08

7. Mechanisms of passive sensitization. I. Presence of IgE and IgG molecules on human leukocytes.

Authors: K Ishizaka; H Tomioka; T Ishizaka
Journal: J Immunol Date: 1970-12 Impact factor: 5.422

8. Calcium ionophores and movement of calcium ions following the physiological stimulus to a secretory process.

Authors: J C Foreman; J L Mongar; B D Gomperts
Journal: Nature Date: 1973-10-05 Impact factor: 49.962

9. The action of lanthanum and manganese on anaphylactic histamine secretion.

Authors: J C Foreman; J L Mongar
Journal: Br J Pharmacol Date: 1973-07 Impact factor: 8.739

10. IgE and IgGa antibody-mediated release of histamine from rat peritoneal cells. I. Optimum conditions for in vitro preparation of target cells with antibody and and challenge with antigen.

Authors: M K Bach; K J Bloch; K F Austen
Journal: J Exp Med Date: 1971-04-01 Impact factor: 14.307

24 in total

8. Restoration of Ca2+ influx and degranulation capacity of variant RBL-2H3 cells upon implantation of isolated cromolyn binding protein.

Authors: N Mazurek; P Bashkin; A Loyter; I Pecht
Journal: Proc Natl Acad Sci U S A Date: 1983-10 Impact factor: 11.205

9. Comparative effects of oxatomide on the release of histamine from rat peritoneal mast cells.

Authors: F De Clerck; J Van Reempts; M Borgers
Journal: Agents Actions Date: 1981-05

10. Oxatomide protects against degranulation of rat peritoneal mast cells during in vitro challenge with antigen or compound 48/80. Ultrastructural aspects.

Authors: J Van Reempts; F De Clerck; M Borgers
Journal: Agents Actions Date: 1981-05

Induction of calcium flux across the rat mast cell membrane by bridging IgE receptors.

1. REAGIN-LIKE ANTIBODIES IN ANIMALS IMMUNE TO HELMINTH PARASITES.

2. The effect of calcium and pH on the anaphylactic reaction.

3. Triggering of cultured neoplastic mast cells by antibodies to the receptor for IgE.

4. Release of histamine and slow reacting substance of anaphylaxis (SRS-A) by IgE-anti-IgE reactions on monkey mast cells.

5. Phosphatidylserine: selective enhancer of histamine release.

6. Biologic function of the Fc fragments of E myeloma protein.

7. Mechanisms of passive sensitization. I. Presence of IgE and IgG molecules on human leukocytes.

8. Calcium ionophores and movement of calcium ions following the physiological stimulus to a secretory process.

9. The action of lanthanum and manganese on anaphylactic histamine secretion.

10. IgE and IgGa antibody-mediated release of histamine from rat peritoneal cells. I. Optimum conditions for in vitro preparation of target cells with antibody and and challenge with antigen.

1. Antigen-induced increase in protein kinase C activity in plasma membrane of mast cells.

2. Rapid phosphorylation of a 92,000 MW protein on activation of rat basophilic leukaemia cells for histamine release.

3. Protein and diacylglycerol phosphorylation in the stimulus-secretion coupling of rat mast cells.

4. Characteristics of histamine release from rat mast cells in relation to the valency of the stimulating ligand.

5. Inhibitory effects of dapsone on enzymatic activities of membrane phospholipids in human blood cells.

6. Characteristics of the effect of phorbol ester on rat mast cells: interaction with anti-IgE.

7. Bridging of IgE receptors activates phospholipid methylation and adenylate cyclase in mast cell plasma membranes.

8. Restoration of Ca2+ influx and degranulation capacity of variant RBL-2H3 cells upon implantation of isolated cromolyn binding protein.

9. Comparative effects of oxatomide on the release of histamine from rat peritoneal mast cells.

10. Oxatomide protects against degranulation of rat peritoneal mast cells during in vitro challenge with antigen or compound 48/80. Ultrastructural aspects.