| Literature DB >> 4100657 |
M K Bach, K J Bloch, K F Austen.
Abstract
The optimum conditions for antigen-induced release of histamine in the rat IgE and IgGa antibody-mediated systems were studied in vitro. The IgE antibody-mediated reaction could be separated into two steps: preparation of target cells with antibody and challenge with antigen. The optimal conditions for these two steps were distinctly different. Release of histamine by IgGa antibody and antigen could not be separated into two steps, and the optimal conditions for the total reaction were identical to those of the antigen challenge step of the IgE antibody-mediated system.Entities:
Mesh:
Substances:
Year: 1971 PMID: 4100657 PMCID: PMC2138970 DOI: 10.1084/jem.133.4.752
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307