J Aarbakke1, G Janka-Schaub, G B Elion. Show Affiliations » 1. Department of Pharmacology, Institute of Medical Biology, University of Tromsø, Norway.
Abstract
Entities: Chemical
Mesh: See more » AnimalsAntimetabolites, Antineoplastic/metabolismAntimetabolites, Antineoplastic/pharmacologyAntimetabolites, Antineoplastic/therapeutic useAzathioprine/chemistryAzathioprine/metabolismAzathioprine/pharmacologyCloning, MolecularGenotypeHumansImmunosuppressive Agents/chemistryImmunosuppressive Agents/metabolismImmunosuppressive Agents/pharmacologyMercaptopurine/metabolismMercaptopurine/pharmacologyMercaptopurine/therapeutic useMethyltransferases/deficiencyMethyltransferases/geneticsMethyltransferases/metabolismMicePolymorphism, Genetic/geneticsPrecursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapyPrecursor Cell Lymphoblastic Leukemia-Lymphoma/geneticsPrecursor Cell Lymphoblastic Leukemia-Lymphoma/metabolismPurines/chemistryPurines/metabolismStructure-Activity RelationshipThioguanine/metabolismThioguanine/pharmacologyThioguanine/therapeutic use
Substances: See more » Antimetabolites, AntineoplasticImmunosuppressive AgentsPurinesMercaptopurineMethyltransferasesthiopurine methyltransferaseThioguanineAzathioprine
Year: 1997 PMID: 9114722 DOI: 10.1016/s0165-6147(96)01007-3
Source DB: PubMed Journal: Trends Pharmacol Sci ISSN: 0165-6147 Impact factor: 14.819