Literature DB >> 19476376

Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancer.

William B Parker1.   

Abstract

Entities:  

Mesh:

Substances:

Year:  2009        PMID: 19476376      PMCID: PMC2827868          DOI: 10.1021/cr900028p

Source DB:  PubMed          Journal:  Chem Rev        ISSN: 0009-2665            Impact factor:   60.622


× No keyword cloud information.
  97 in total

Review 1.  Prodrug-activating systems in suicide gene therapy.

Authors:  C J Springer; I Niculescu-Duvaz
Journal:  J Clin Invest       Date:  2000-05       Impact factor: 14.808

2.  Incorporation of OSI-7836 into DNA of Calu-6 and H460 xenograft tumors.

Authors:  Frank Richardson; Chris Black; Katherine Richardson; April Franks; Edward Wells; Susan Karimi; Gina Sennello; Karen Hart; Denny Meyer; David Emerson; Eric Brown; Jeremy LeRay; Christy Nilsson; Blake Tomkinson; Raymond Bendele
Journal:  Cancer Chemother Pharmacol       Date:  2004-11-16       Impact factor: 3.333

3.  Sequence-specific effects of ara-5-aza-CTP and ara-CTP on DNA synthesis by purified human DNA polymerases in vitro: visualization of chain elongation on a defined template.

Authors:  A J Townsend; Y C Cheng
Journal:  Mol Pharmacol       Date:  1987-09       Impact factor: 4.436

Review 4.  Cladribine in the treatment of hairy-cell leukaemia.

Authors:  Grant R Goodman; Ernest Beutler; Alan Saven
Journal:  Best Pract Res Clin Haematol       Date:  2003-03       Impact factor: 3.020

5.  Arabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase and mitochondrial deoxyguanosine kinase.

Authors:  Carlos O Rodriguez; Beverly S Mitchell; Mary Ayres; Staffan Eriksson; Varsha Gandhi
Journal:  Cancer Res       Date:  2002-06-01       Impact factor: 12.701

Review 6.  Metabolism and mechanism of action of 5-fluorouracil.

Authors:  W B Parker; Y C Cheng
Journal:  Pharmacol Ther       Date:  1990       Impact factor: 12.310

7.  2'-Deoxy-6-thioguanosine 5'-triphosphate as a substrate for purified human DNA polymerases and calf thymus terminal deoxynucleotidyltransferase in vitro.

Authors:  Y H Ling; J A Nelson; Y C Cheng; R S Anderson; K L Beattie
Journal:  Mol Pharmacol       Date:  1991-10       Impact factor: 4.436

8.  Selective toxicity of deoxyguanosine and arabinosyl guanine for T-leukemic cells.

Authors:  A Cohen; J W Lee; E W Gelfand
Journal:  Blood       Date:  1983-04       Impact factor: 22.113

9.  Repair of 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine-induced DNA single-strand breaks by transcription-coupled nucleotide excision repair.

Authors:  Yaqing Wang; Xiaojun Liu; Akira Matsuda; William Plunkett
Journal:  Cancer Res       Date:  2008-05-15       Impact factor: 12.701

10.  Metabolism and metabolic actions of 6-methylpurine and 2-fluoroadenine in human cells.

Authors:  W B Parker; P W Allan; S C Shaddix; L M Rose; H F Speegle; G Y Gillespie; L L Bennett
Journal:  Biochem Pharmacol       Date:  1998-05-15       Impact factor: 5.858

View more
  80 in total

1.  Synthesis of 2'-deoxy-9-deaza nucleosides using Heck methodology.

Authors:  Kartik Temburnikar; Kelin Brace; Katherine L Seley-Radtke
Journal:  J Org Chem       Date:  2013-07-05       Impact factor: 4.354

2.  Nucleotide Analogues as Probes for DNA and RNA Polymerases.

Authors:  Robert D Kuchta
Journal:  Curr Protoc Chem Biol       Date:  2010

3.  Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway.

Authors:  Jan Balzarini; Federico Gago; Wim Kulik; André B P van Kuilenburg; Anna Karlsson; Matt A Peterson; Morris J Robins
Journal:  J Biol Chem       Date:  2012-06-24       Impact factor: 5.157

4.  Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases.

Authors:  Alessio Nocentini; Silvia Bua; Carrie L Lomelino; Robert McKenna; Marta Menicatti; Gianluca Bartolucci; Barbara Tenci; Lorenzo Di Cesare Mannelli; Carla Ghelardini; Paola Gratteri; Claudiu T Supuran
Journal:  ACS Med Chem Lett       Date:  2017-11-21       Impact factor: 4.345

5.  A non-natural nucleoside with combined therapeutic and diagnostic activities against leukemia.

Authors:  Edward A Motea; Irene Lee; Anthony J Berdis
Journal:  ACS Chem Biol       Date:  2012-03-13       Impact factor: 5.100

6.  Comparative studies of cellular viability levels on 2D and 3D in vitro culture matrices.

Authors:  M Gargotti; U Lopez-Gonzalez; H J Byrne; A Casey
Journal:  Cytotechnology       Date:  2017-09-18       Impact factor: 2.058

7.  Systemic delivery of gemcitabine triphosphate via LCP nanoparticles for NSCLC and pancreatic cancer therapy.

Authors:  Yuan Zhang; William Y Kim; Leaf Huang
Journal:  Biomaterials       Date:  2013-02-04       Impact factor: 12.479

8.  Use of Drosophila deoxynucleoside kinase to study mechanism of toxicity and mutagenicity of deoxycytidine analogs in Escherichia coli.

Authors:  Brittany Betham; Sophia Shalhout; Victor E Marquez; Ashok S Bhagwat
Journal:  DNA Repair (Amst)       Date:  2009-12-11

9.  Use of E. coli Purine Nucleoside Phosphorylase in the Treatment of Solid Tumors.

Authors:  William B Parker; Eric J Sorscher
Journal:  Curr Pharm Des       Date:  2017-11-08       Impact factor: 3.116

10.  Targeting cancer metabolism.

Authors:  Beverly A Teicher; W Marston Linehan; Lee J Helman
Journal:  Clin Cancer Res       Date:  2012-10-15       Impact factor: 12.531

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.