Literature DB >> 12697731

Azathioprine: old drug, new actions.

Jonathan S Maltzman1, Gary A Koretzky.   

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Year:  2003        PMID： 12697731      PMCID： PMC152947          DOI： 10.1172/JCI18384

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


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  20 in total

1.  Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.

Authors:  A D Wells; X C Li; Y Li; M C Walsh; X X Zheng; Z Wu; G Nuñez; A Tang; M Sayegh; W W Hancock; T B Strom; L A Turka
Journal:  Nat Med       Date:  1999-11       Impact factor: 53.440

2.  CD28 signaling via VAV/SLP-76 adaptors: regulation of cytokine transcription independent of TCR ligation.

Authors:  M Raab; S Pfister; C E Rudd
Journal:  Immunity       Date:  2001-12       Impact factor: 31.745

Review 3.  Pathways of apoptosis in lymphocyte development, homeostasis, and disease.

Authors:  Jeffrey C Rathmell; Craig B Thompson
Journal:  Cell       Date:  2002-04       Impact factor: 41.582

Review 4.  Activation and inhibition of lymphocytes by costimulation.

Authors:  Kenneth A Frauwirth; Craig B Thompson
Journal:  J Clin Invest       Date:  2002-02       Impact factor: 14.808

5.  A point mutation in CD28 distinguishes proliferative signals from survival signals.

Authors:  K Okkenhaug; L Wu; K M Garza; J La Rose; W Khoo; B Odermatt; T W Mak; P S Ohashi; R Rottapel
Journal:  Nat Immunol       Date:  2001-04       Impact factor: 25.606

6.  Prolonged survival of human-kidney homografts by immunosuppressive drug therapy.

Authors:  J E MURRAY; J P MERRILL; J H HARRISON; R E WILSON; G J DAMMIN
Journal:  N Engl J Med       Date:  1963-06-13       Impact factor: 91.245

7.  Vav cooperates with CD28 to induce NF-kappaB activation via a pathway involving Rac-1 and mitogen-activated kinase kinase 1.

Authors:  Barbara Marinari; Antonio Costanzo; Antonella Viola; Frederique Michel; Giorgio Mangino; Oreste Acuto; Massimo Levrero; Enza Piccolella; Loretta Tuosto
Journal:  Eur J Immunol       Date:  2002-02       Impact factor: 5.532

8.  Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL.

Authors:  J S Burr; N D Savage; G E Messah; S L Kimzey; A S Shaw; R H Arch; J M Green
Journal:  J Immunol       Date:  2001-05-01       Impact factor: 5.422

9.  The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes.

Authors:  A Khoshnan; C Tindell; I Laux; D Bae; B Bennett; A E Nel
Journal:  J Immunol       Date:  2000-08-15       Impact factor: 5.422

10.  Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia.

Authors:  B J Druker; M Talpaz; D J Resta; B Peng; E Buchdunger; J M Ford; N B Lydon; H Kantarjian; R Capdeville; S Ohno-Jones; C L Sawyers
Journal:  N Engl J Med       Date:  2001-04-05       Impact factor: 91.245
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  67 in total

1.  NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity.

Authors:  Takaya Moriyama; Rina Nishii; Virginia Perez-Andreu; Wenjian Yang; Federico Antillon Klussmann; Xujie Zhao; Ting-Nien Lin; Keito Hoshitsuki; Jacob Nersting; Kentaro Kihira; Ute Hofmann; Yoshihiro Komada; Motohiro Kato; Robert McCorkle; Lie Li; Katsuyoshi Koh; Cesar Rolando Najera; Shirley Kow-Yin Kham; Tomoya Isobe; Zhiwei Chen; Edwynn Kean-Hui Chiew; Deepa Bhojwani; Cynthia Jeffries; Yan Lu; Matthias Schwab; Hiroto Inaba; Ching-Hon Pui; Mary V Relling; Atsushi Manabe; Hiroki Hori; Kjeld Schmiegelow; Allen E J Yeoh; William E Evans; Jun J Yang
Journal:  Nat Genet       Date:  2016-02-15       Impact factor: 38.330

2.  Deciphering the Function of New Gonococcal Vaccine Antigens Using Phenotypic Microarrays.

Authors:  Benjamin I Baarda; Sarah Emerson; Philip J Proteau; Aleksandra E Sikora
Journal:  J Bacteriol       Date:  2017-08-08       Impact factor: 3.490

3.  Azathioprine suppresses ezrin-radixin-moesin-dependent T cell-APC conjugation through inhibition of Vav guanosine exchange activity on Rac proteins.

Authors:  Daniela Poppe; Imke Tiede; Gerhard Fritz; Christoph Becker; Brigitte Bartsch; Stefan Wirtz; Dennis Strand; Shinya Tanaka; Peter R Galle; Xosé R Bustelo; Markus F Neurath
Journal:  J Immunol       Date:  2006-01-01       Impact factor: 5.422

Review 4.  Treatment of Eczema: Corticosteroids and Beyond.

Authors:  Melanie Chong; Luz Fonacier
Journal:  Clin Rev Allergy Immunol       Date:  2016-12       Impact factor: 8.667

Review 5.  Immunology of idiopathic nephrotic syndrome.

Authors:  Manuela Colucci; Giorgia Corpetti; Francesco Emma; Marina Vivarelli
Journal:  Pediatr Nephrol       Date:  2017-04-27       Impact factor: 3.714

6.  Targeting Pancreatic Cancer Metastasis by Inhibition of Vav1, a Driver of Tumor Cell Invasion.

Authors:  Gina L Razidlo; Christopher Magnine; Arthur C Sletten; Rachel M Hurley; Luciana L Almada; Martin E Fernandez-Zapico; Baoan Ji; Mark A McNiven
Journal:  Cancer Res       Date:  2015-05-14       Impact factor: 12.701

Review 7.  Medical management of crohn disease.

Authors:  Frank I Scott; Mark T Osterman
Journal:  Clin Colon Rectal Surg       Date:  2013-06

8.  Massively parallel variant characterization identifies NUDT15 alleles associated with thiopurine toxicity.

Authors:  Chase C Suiter; Takaya Moriyama; Kenneth A Matreyek; Wentao Yang; Emma Rose Scaletti; Rina Nishii; Wenjian Yang; Keito Hoshitsuki; Minu Singh; Amita Trehan; Chris Parish; Colton Smith; Lie Li; Deepa Bhojwani; Liz Y P Yuen; Chi-Kong Li; Chak-Ho Li; Yung-Li Yang; Gareth J Walker; James R Goodhand; Nicholas A Kennedy; Federico Antillon Klussmann; Smita Bhatia; Mary V Relling; Motohiro Kato; Hiroki Hori; Prateek Bhatia; Tariq Ahmad; Allen E J Yeoh; Pål Stenmark; Douglas M Fowler; Jun J Yang
Journal:  Proc Natl Acad Sci U S A       Date:  2020-02-24       Impact factor: 11.205

9.  Risk factors for symptomatic osteonecrosis in childhood ALL: A retrospective study of a Slovenian pediatric ALL population between 1970 and 2004.

Authors:  Nataša Karas-Kuželički; Simona Mencej-Bedrač; Janez Jazbec; Janja Marc; Irena Mlinarič-Raščan
Journal:  Exp Ther Med       Date:  2016-05-25       Impact factor: 2.447

Review 10.  New molecular targets for the treatment of sarcoidosis.

Authors:  Jared Chiarchiaro; Bill B Chen; Kevin F Gibson
Journal:  Curr Opin Pulm Med       Date:  2016-09       Impact factor: 3.155
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