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Literature DB >> 8920177

Lantibiotic nisin Z fermentative production by Lactococcus lactis IO-1: relationship between production of the lantibiotic and lactate and cell growth.

H Matsusaki¹, N Endo, K Sonomoto, A Ishizaki.

Abstract

The influence of several parameters on the fermentative production of nisin Z by Lactococcus lactis IO-1 was studied. Considerable attention has been focused on the relationship between the primary metabolite production of bacteriocin and lactate and cell growth, which has so far not been clarified in detail. Production of nisin Z was optimal at 30 degrees C and in the pH range 5.0-5.5. The addition of Ca2+ to the medium showed a stimulating effect on the production of nisin Z. A maximum activity of 3150 IU/ml was obtained during pH-controlled batch fermentation in the medium supplemented with 0.1 M CaCl2. It was about three times higher than that obtained under the optimal conditions for cell growth and lactic acid production.

Entities: Chemical Species

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Year: 1996 PMID： 8920177 DOI： 10.1007/s002530050645

Source DB: PubMed Journal: Appl Microbiol Biotechnol ISSN： 0175-7598 Impact factor: 4.813

11 in total

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25 in total

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Authors: R Callewaert; L De Vuyst
Journal: Appl Environ Microbiol Date: 2000-02 Impact factor: 4.792

2. Purification and characterization of a novel bacteriocin produced by Enterococcus faecalis strain RJ-11.

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Journal: Appl Environ Microbiol Date: 2003-10 Impact factor: 4.792

3. Production and characterization of nisin-like peptide produced by a strain of Lactococcus lactis isolated from fermented milk.

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Journal: Curr Microbiol Date: 2005-07-21 Impact factor: 2.188

4. Nisin production by a mixed-culture system consisting of Lactococcus lactis and Kluyveromyces marxianus.

Authors: H Shimizu; T Mizuguchi; E Tanaka; S Shioya
Journal: Appl Environ Microbiol Date: 1999-07 Impact factor: 4.792

5. Influence of Environmental Factors on Bacteriocin Production by Human Isolates of Lactococcus lactis MM19 and Pediococcus acidilactici MM33.

Authors: Mélanie Turgis; Khanh Dang Vu; Mathieu Millette; Claude Dupont; Monique Lacroix
Journal: Probiotics Antimicrob Proteins Date: 2016-03 Impact factor: 4.609

6. Identification of Lactococcus-Specific Bacteriocins Produced by Lactococcal Isolates, and the Discovery of a Novel Bacteriocin, Lactococcin Z.

Authors: Naoki Ishibashi; Hiromi Seto; Shoko Koga; Takeshi Zendo; Kenji Sonomoto
Journal: Probiotics Antimicrob Proteins Date: 2015-09 Impact factor: 4.609