R N Chen1, S B Streem. 1. Department of Urology, Cleveland Clinic Foundation, Ohio 44195, USA.
Abstract
PURPOSE: We evaluated the efficacy of extracorporeal shock wave lithotripsy (ESWL) for lower pole calculi regarding immediate and long-term radiographic and clinical outcomes. MATERIALS AND METHODS: A total of 206 patients with isolated lower pole calculi in 220 renal units underwent ESWL for stones 4 to 625 mm2 (mean 88). Clinical and radiographic followup was obtained at 1 month and every 6 to 12 months thereafter. An initial stone-free rate was determined, as was the subsequent radiographic outcome. Clinical outcome with regard to a symptomatic episode or requiring intervention was also determined. Kaplan-Meier estimates of the probabilities of these outcomes with time were developed. RESULTS: Of the 206 patients 99 (48%) were rendered stone-free by 1 month after ESWL. Another 13 patients (6.3%) spontaneously became stone-free within another 1 to 95 months (mean 17.5). Of the remaining patients residual stones were decreased, stable or increased in 13 (6.3%), 71 (34%) and 10 (4.8%), respectively, after 1 to 91 months (mean 14.5). Among all 206 patients 180 (87.4%) remained asymptomatic for 1 to 99 months, while 7 (3.4%) suffered a symptomatic episode requiring medical attention 1 to 40 months (mean 21.1) after ESWL and 19 (9.2%) required intervention after 1 to 91 months (mean 23.9). Kaplan-Meier estimates of the probabilities of a symptomatic episode or requiring intervention at 5 years were 0.24 and 0.52, respectively. CONCLUSIONS: ESWL is the initial treatment of choice for lower pole calculi smaller than 2 cm.2 because the stone-free rate is comparable to that for stones at other caliceal locations and, perhaps more importantly, the risk of a symptomatic episode or requiring secondary intervention is low even in the setting of residual fragments.
PURPOSE: We evaluated the efficacy of extracorporeal shock wave lithotripsy (ESWL) for lower pole calculi regarding immediate and long-term radiographic and clinical outcomes. MATERIALS AND METHODS: A total of 206 patients with isolated lower pole calculi in 220 renal units underwent ESWL for stones 4 to 625 mm2 (mean 88). Clinical and radiographic followup was obtained at 1 month and every 6 to 12 months thereafter. An initial stone-free rate was determined, as was the subsequent radiographic outcome. Clinical outcome with regard to a symptomatic episode or requiring intervention was also determined. Kaplan-Meier estimates of the probabilities of these outcomes with time were developed. RESULTS: Of the 206 patients 99 (48%) were rendered stone-free by 1 month after ESWL. Another 13 patients (6.3%) spontaneously became stone-free within another 1 to 95 months (mean 17.5). Of the remaining patients residual stones were decreased, stable or increased in 13 (6.3%), 71 (34%) and 10 (4.8%), respectively, after 1 to 91 months (mean 14.5). Among all 206 patients 180 (87.4%) remained asymptomatic for 1 to 99 months, while 7 (3.4%) suffered a symptomatic episode requiring medical attention 1 to 40 months (mean 21.1) after ESWL and 19 (9.2%) required intervention after 1 to 91 months (mean 23.9). Kaplan-Meier estimates of the probabilities of a symptomatic episode or requiring intervention at 5 years were 0.24 and 0.52, respectively. CONCLUSIONS: ESWL is the initial treatment of choice for lower pole calculi smaller than 2 cm.2 because the stone-free rate is comparable to that for stones at other caliceal locations and, perhaps more importantly, the risk of a symptomatic episode or requiring secondary intervention is low even in the setting of residual fragments.
Authors: Anup Shah; Neil R Owen; Wei Lu; Bryan W Cunitz; Peter J Kaczkowski; Jonathan D Harper; Michael R Bailey; Lawrence A Crum Journal: Urol Res Date: 2010-10-22
Authors: Jonathan D Harper; Mathew D Sorensen; Bryan W Cunitz; Yak-Nam Wang; Julianna C Simon; Frank Starr; Marla Paun; Barbrina Dunmire; H Denny Liggitt; Andrew P Evan; James A McAteer; Ryan S Hsi; Michael R Bailey Journal: J Urol Date: 2013-04-09 Impact factor: 7.450
Authors: Bret A Connors; Andrew P Evan; Philip M Blomgren; Ryan S Hsi; Jonathan D Harper; Mathew D Sorensen; Yak-Nam Wang; Julianna C Simon; Marla Paun; Frank Starr; Bryan W Cunitz; Michael R Bailey; James E Lingeman Journal: J Urol Date: 2013-08-02 Impact factor: 7.450