Literature DB >> 883813

Human interferon: mass production in a newly established cell line, MG-63.

A Billiau, V G Edy, H Heremans, J Van Damme, J Desmyter, J A Georgiades, P De Somer.   

Abstract

MG-63 cells, a line derived from an osteosarcoma, produced high yields of interferon after superinduction with polyinosinic acid.polycytidylic acid, cycloheximide, and actinomycin D. Advantages of MG-63 cells over diploid fibroblasts as a substrate are: no requirement for aging between confluency and induction, no requirement for priming, and 3.7-fold higher yields per square centimeter of culture surface. Physicochemically and biologically, MG-63 cell interferon resembles fibroblast rather than leukocyte interferon.

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Year:  1977        PMID： 883813      PMCID： PMC352146          DOI： 10.1128/AAC.12.1.11

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  14 in total

1.  Purification of interferon by adsorption chromatography on controlled pore glass.

Authors:  V G Edy; I A Braude; E De Clercq; A Billiau; P De Somer
Journal:  J Gen Virol       Date:  1976-12       Impact factor: 3.891

2.  Production of human lymphoblastoid interferon.

Authors:  H Strander; K E Mogensen; K Cantell
Journal:  J Clin Microbiol       Date:  1975-01       Impact factor: 5.948

3.  Mass production of human interferon in diploid cells stimulated by poly-I:C.

Authors:  A Billiau; M Joniau; P De Somer
Journal:  J Gen Virol       Date:  1973-04       Impact factor: 3.891

4.  Pronounced antiviral activity of human interferon on bovine and porcine cells.

Authors:  I Gresser; M T Bandu; D Brouty-boye; M Tovey
Journal:  Nature       Date:  1974-10-11       Impact factor: 49.962

5.  Mass production of human interferon in diploid cells.

Authors:  P De Somer; M Joniau; V G Edy; A Billiau
Journal:  In Vitro Monogr       Date:  1974

6.  The somatic cell genetics of human interferon: assignment of human interferon loci to chromosomes 2 and 5.

Authors:  Y H Tan; R P Creagan; F H Ruddle
Journal:  Proc Natl Acad Sci U S A       Date:  1974-06       Impact factor: 11.205

Review 7.  Human leukocyte interferon: production, purification, stability, and animal experiments.

Authors:  K Cantell; S Hirvonen; K E Mogensen; L Pyhälä
Journal:  In Vitro Monogr       Date:  1974

8.  Regulation of cellular interferon production: enhancement by antimetabolites.

Authors:  Y H Tan; J A Armstrong; Y H Ke; M Ho
Journal:  Proc Natl Acad Sci U S A       Date:  1970-09       Impact factor: 11.205

9.  Two antigenically distinct species of human interferon.

Authors:  E A Havell; B Berman; C A Ogburn; K Berg; K Paucker; J Vilcek
Journal:  Proc Natl Acad Sci U S A       Date:  1975-06       Impact factor: 11.205

10.  Administration of human fibroblast interferon in chronic hepatitis-B infection.

Authors:  J Desmyter; J De Groote; V J Desmet; A Billiau; M B Ray; A F Bradburne; V G Edy; P De Somer
Journal:  Lancet       Date:  1976-09-25       Impact factor: 79.321
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  64 in total

Review 1.  Do you know the sex of your cells?

Authors:  Kalpit Shah; Charles E McCormack; Neil A Bradbury
Journal:  Am J Physiol Cell Physiol       Date:  2013-11-06       Impact factor: 4.249

2.  [In vitro trials with single and co-cultures of osteoblasts and endothelial cells : evaluation of new biomaterials for bone reconstruction and regeneration].

Authors:  R E Unger; S Halstenberg; H Günther; A Sartoris; C Brochhausen; C J Kirkpatrick
Journal:  Orthopade       Date:  2009-11       Impact factor: 1.087

3.  A novel in vitro three-dimensional skeletal muscle model.

Authors:  Michele L Marquette; Diane Byerly; Marguerite Sognier
Journal:  In Vitro Cell Dev Biol Anim       Date:  2007-09-05       Impact factor: 2.416

4.  Runx2 expression: A mesenchymal stem marker for cancer.

Authors:  Maria Teresa Valenti; Paola Serafini; Giulio Innamorati; Anna Gili; Samuele Cheri; Claudio Bassi; Luca Dalle Carbonare
Journal:  Oncol Lett       Date:  2016-09-23       Impact factor: 2.967

5.  Activation of the human beta-interferon gene requires an interferon-inducible factor.

Authors:  T Enoch; K Zinn; T Maniatis
Journal:  Mol Cell Biol       Date:  1986-03       Impact factor: 4.272

6.  Large-scale production and concentration of human lymphoid interferon.

Authors:  F Klein; R T Ricketts; W I Jones; I A DeArmon; M J Temple; K C Zoon; P J Bridgen
Journal:  Antimicrob Agents Chemother       Date:  1979-03       Impact factor: 5.191

7.  Cell cultures producing human interferon.

Authors:  P C Familletti; S Pestka
Journal:  Antimicrob Agents Chemother       Date:  1981-07       Impact factor: 5.191

8.  Time-lapse microscopic observation of non-dividing cells in cultured human osteosarcoma MG-63 cell line.

Authors:  John Dosch; Elise Hadley; Cal Wiese; Marissa Soderberg; Tori Houwman; Kai Ding; Alexandra Kharazova; John L Collins; Bart van Knippenberg; Carl Gregory; Alexander Kofman
Journal:  Cell Cycle       Date:  2017-12-26       Impact factor: 4.534

9.  Simultaneous gene expression analysis of steady-state and actively translated mRNA populations from osteosarcoma MG-63 cells in response to IL-1alpha via an open expression analysis platform.

Authors:  Jingfang Ju; Chunli Huang; Stacey A Minskoff; Jane E Mayotte; Bruce E Taillon; Jan F Simons
Journal:  Nucleic Acids Res       Date:  2003-09-01       Impact factor: 16.971

10.  Organization of the amplified type I interferon gene cluster and associated chromosome regions in the interphase nucleus of human osteosarcoma cells.

Authors:  Michael J Zeitz; Narasimharao V Marella; Kishore S Malyavantham; Sandra Goetze; Juergen Bode; Ivan Raska; Ronald Berezney
Journal:  Chromosome Res       Date:  2009-03-13       Impact factor: 5.239
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