| Literature DB >> 8835527 |
P A Baldacci1, M Cohen-Tannoudji, C Kress, S Pournin, C Babinet.
Abstract
The locus Om (ovum mutant) identified in the mouse strain DDK affects the viability of (DDK x non-DDK)F1 preimplantation embryos. We previously located this locus on Chromosome (Chr) 11 close to Scya2 (Baldacci et al. Mamm. Genome 2, 100-105, 1992). Here we report a high-resolution map of the region around Om based on a large number of backcross individuals. The same region has been analyzed on the EUCIB backcross, and the two maps have been compared. The results define the proximal and distal boundaries for the Om mutation as Scya2 and D11Mit36 respectively. The distance between these two markers is about 2 cM. These data should facilitate the positional cloning and molecular characterization of Om.Entities:
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Year: 1996 PMID: 8835527 DOI: 10.1007/s003359900030
Source DB: PubMed Journal: Mamm Genome ISSN: 0938-8990 Impact factor: 2.957