Literature DB >> 4086787

Confidence limits for estimates of gene linkage based on analysis of recombinant inbred strains.

J Silver.   

Abstract

Recombinant inbred (RI) strains are extremely useful for genetic mapping. This paper presents a simple method for determining confidence intervals for linkage estimates based on analysis of RI strains. The results show that such confidence intervals are usually large with the currently available numbers of RI strains. Therefore, map positions based only on analysis of RI strains should be interpreted with caution. To facilitate interpretation of linkage data derived from RI strains, a table is presented giving the 95 percent and 99 percent confidence intervals for all possible linkages detected with up to 45 RI strains.

Mesh：

Year:  1985        PMID： 4086787     DOI： 10.1093/oxfordjournals.jhered.a110140

Source DB:  PubMed          Journal:  J Hered        ISSN： 0022-1503            Impact factor:   2.645


  116 in total

1.  Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster.

Authors:  S V Nuzhdin; E G Pasyukova; C L Dilda; Z B Zeng; T F Mackay
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-02       Impact factor: 11.205

2.  Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice.

Authors:  K J Buck; P Metten; J K Belknap; J C Crabbe
Journal:  J Neurosci       Date:  1997-05-15       Impact factor: 6.167

3.  Close linkage of retinoic acid receptor genes with homeobox- and keratin-encoding genes on paralogous segments of mouse chromosomes 11 and 15.

Authors:  J H Nadeau; J G Compton; V Giguère; J Rossant; S Varmuza
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

4.  The gene for the POU domain transcription factor Oct-6 maps to the distal end of mouse chromosome 4.

Authors:  H Rohdewohld; P Gruss
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

5.  Plasma cell membrane glycoprotein gene Pca-1 (alkaline phosphodiesterase I) is linked to the proto-oncogene Myb on mouse chromosome 10.

Authors:  M F Buckley; J W Goding
Journal:  Immunogenetics       Date:  1992       Impact factor: 2.846

6.  Mapping of the genes encoding tum- transplantation antigens P91A, P35B, and P198.

Authors:  P J Dyson; C de Smet; A M Knight; D Simon-Chazottes; J L Guénet; T Boon
Journal:  Immunogenetics       Date:  1992       Impact factor: 2.846

7.  Chromosomal localization of the murine stress protein gene encoding glucose-regulated protein 78 (BiP).

Authors:  H R Gaskins; M Prochazka; E H Leiter
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 8.  Mouse chromosome 2.

Authors:  L D Siracusa; C M Abbott
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

9.  Multilocus markers for mouse genome analysis: PCR amplification based on single primers of arbitrary nucleotide sequence.

Authors:  J H Nadeau; H G Bedigian; G Bouchard; T Denial; M Kosowsky; R Norberg; S Pugh; E Sargeant; R Turner; B Paigen
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

10.  Localization of murine HLH gene NSCL to chromosome 1 by use of recombinant inbred strains.

Authors:  N M Gough; S Lipkowitz; I R Kirsch; C G Begley
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957
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