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Literature DB >> 8792461

On the parameters of the clonal expansion model.

Abstract

The exact hazard function of the clonal expansion model was analyzed, and it was shown that only three of its four parameters can be determined by fitting to the age dependence of spontaneous tumor incidence rates. The same holds for the survival function.

Entities: Disease

Mesh：

Year: 1996 PMID： 8792461 DOI： 10.1007/bf02434036

Source DB: PubMed Journal: Radiat Environ Biophys ISSN： 0301-634X Impact factor: 1.925

5 in total

Review 1. Two-event model for carcinogenesis: biological, mathematical, and statistical considerations.

Authors: S H Moolgavkar; G Luebeck
Journal: Risk Anal Date: 1990-06 Impact factor: 4.000

2. The exact formula for tumor incidence in the two-stage model.

Authors: A Kopp-Schneider; C J Portier; C D Sherman
Journal: Risk Anal Date: 1994-12 Impact factor: 4.000

3. Armitage-Doll two-stage model: implications and extension.

Authors: C W Chen
Journal: Risk Anal Date: 1993-06 Impact factor: 4.000

4. On the exact hazard and survival functions of the MVK stochastic carcinogenesis model.

Authors: Q Zheng
Journal: Risk Anal Date: 1994-12 Impact factor: 4.000

5. A two-stage theory of carcinogenesis in relation to the age distribution of human cancer.

Authors: P ARMITAGE; R DOLL
Journal: Br J Cancer Date: 1957-06 Impact factor: 7.640

5 in total

21 in total

1. Breast cancer risk in atomic bomb survivors from multi-model inference with incidence data 1958-1998.

Authors: J C Kaiser; P Jacob; R Meckbach; H M Cullings
Journal: Radiat Environ Biophys Date: 2011-09-23 Impact factor: 1.925

2. Lung cancer mortality in the European uranium miners cohorts analyzed with a biologically based model taking into account radon measurement error.

Authors: W F Heidenreich; L Tomasek; B Grosche; K Leuraud; D Laurier
Journal: Radiat Environ Biophys Date: 2012-05-24 Impact factor: 1.925

3. Comparison of mortality and incidence solid cancer risk after radiation exposure in the Techa River Cohort.

Authors: M Eidemüller; E Ostroumova; L Krestinina; S Epiphanova; A Akleyev; P Jacob
Journal: Radiat Environ Biophys Date: 2010-05-12 Impact factor: 1.925

4. Studies of radon-exposed miner cohorts using a biologically based model: comparison of current Czech and French data with historic data from China and Colorado.

Authors: W F Heidenreich; L Tomásek; A Rogel; D Laurier; M Tirmarche
Journal: Radiat Environ Biophys Date: 2004-11-30 Impact factor: 1.925

On the parameters of the clonal expansion model.

Review 1. Two-event model for carcinogenesis: biological, mathematical, and statistical considerations.

2. The exact formula for tumor incidence in the two-stage model.

3. Armitage-Doll two-stage model: implications and extension.

4. On the exact hazard and survival functions of the MVK stochastic carcinogenesis model.

5. A two-stage theory of carcinogenesis in relation to the age distribution of human cancer.

1. Breast cancer risk in atomic bomb survivors from multi-model inference with incidence data 1958-1998.

2. Lung cancer mortality in the European uranium miners cohorts analyzed with a biologically based model taking into account radon measurement error.

3. Comparison of mortality and incidence solid cancer risk after radiation exposure in the Techa River Cohort.

4. Studies of radon-exposed miner cohorts using a biologically based model: comparison of current Czech and French data with historic data from China and Colorado.

5. Lung cancer in Mayak workers: interaction of smoking and plutonium exposure.

6. Bone cancer risk in mice exposed to 224Ra: protraction effects from promotion.

7. Parameter identifiability and redundancy: theoretical considerations.

Review 8. Cancer models, genomic instability and somatic cellular Darwinian evolution.

9. A Systematic Approach to Determining the Identifiability of Multistage Carcinogenesis Models.

10. Parameter identifiability and redundancy in a general class of stochastic carcinogenesis models.