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Literature DB >> 8698848

Conditional gene targeting.

K Rajewsky¹, H Gu, R Kühn, U A Betz, W Müller, J Roes, F Schwenk.

Abstract

Mesh：

Substances：

Year: 1996 PMID： 8698848 PMCID： PMC507466 DOI： 10.1172/JCI118828

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

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30 in total

1. Tissue- and site-specific DNA recombination in transgenic mice.

Authors: P C Orban; D Chui; J D Marth
Journal: Proc Natl Acad Sci U S A Date: 1992-08-01 Impact factor: 11.205

Review 2. Altering genes in animals by gene targeting.

Authors: B H Koller; O Smithies
Journal: Annu Rev Immunol Date: 1992 Impact factor: 28.527

3. Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1.

Authors: B Sauer; N Henderson
Journal: Proc Natl Acad Sci U S A Date: 1988-07 Impact factor: 11.205

4. Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells.

Authors: P Hasty; R Ramírez-Solis; R Krumlauf; A Bradley
Journal: Nature Date: 1991-03-21 Impact factor: 49.962

5. Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting.

Authors: H Gu; Y R Zou; K Rajewsky
Journal: Cell Date: 1993-06-18 Impact factor: 41.582

6. Site-specific recombination by the bacteriophage P1 lox-Cre system. Cre-mediated synapsis of two lox sites.

Authors: D L Hamilton; K Abremski
Journal: J Mol Biol Date: 1984-09-15 Impact factor: 5.469

7. Targeted oncogene activation by site-specific recombination in transgenic mice.

Authors: M Lakso; B Sauer; B Mosinger; E J Lee; R W Manning; S H Yu; K L Mulder; H Westphal
Journal: Proc Natl Acad Sci U S A Date: 1992-07-15 Impact factor: 11.205

Review 8. The new mouse genetics: altering the genome by gene targeting.

Authors: M R Capecchi
Journal: Trends Genet Date: 1989-03 Impact factor: 11.639

9. Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells.

Authors: V Valancius; O Smithies
Journal: Mol Cell Biol Date: 1991-03 Impact factor: 4.272

10. The integrase family of site-specific recombinases: regional similarities and global diversity.

Authors: P Argos; A Landy; K Abremski; J B Egan; E Haggard-Ljungquist; R H Hoess; M L Kahn; B Kalionis; S V Narayana; L S Pierson
Journal: EMBO J Date: 1986-02 Impact factor: 11.598

115 in total

1. Efficient gene activation in cultured mammalian cells mediated by FLP recombinase-expressing recombinant adenovirus.

Authors: M Nakano; K Odaka; M Ishimura; S Kondo; N Tachikawa; J Chiba; Y Kanegae; I Saito
Journal: Nucleic Acids Res Date: 2001-04-01 Impact factor: 16.971

Review 2. Demystified ... gene knockouts.

Authors: J P Iredale
Journal: Mol Pathol Date: 1999-06

10. Transgenic mice expressing a ligand-inducible cre recombinase in osteoblasts and odontoblasts: a new tool to examine physiology and disease of postnatal bone and tooth.

Authors: Jung-Eun Kim; Kazuhisa Nakashima; Benoit de Crombrugghe
Journal: Am J Pathol Date: 2004-12 Impact factor: 4.307

Conditional gene targeting.

1. Tissue- and site-specific DNA recombination in transgenic mice.

Review 2. Altering genes in animals by gene targeting.

3. Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1.

4. Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells.

5. Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting.

6. Site-specific recombination by the bacteriophage P1 lox-Cre system. Cre-mediated synapsis of two lox sites.

7. Targeted oncogene activation by site-specific recombination in transgenic mice.

Review 8. The new mouse genetics: altering the genome by gene targeting.

9. Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells.

10. The integrase family of site-specific recombinases: regional similarities and global diversity.

1. Efficient gene activation in cultured mammalian cells mediated by FLP recombinase-expressing recombinant adenovirus.

Review 2. Demystified ... gene knockouts.

3. Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells.

Review 4. Insights into insulin resistance and type 2 diabetes from knockout mouse models.

Review 5. Cre/lox: one more step in the taming of the genome.

6. Stringent doxycycline dependent control of CRE recombinase in vivo.

7. Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice.

8. Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice.

9. Cre recombinase induces DNA damage and tetraploidy in the absence of loxP sites.

10. Transgenic mice expressing a ligand-inducible cre recombinase in osteoblasts and odontoblasts: a new tool to examine physiology and disease of postnatal bone and tooth.