Literature DB >> 6333513

Site-specific recombination by the bacteriophage P1 lox-Cre system. Cre-mediated synapsis of two lox sites.

D L Hamilton, K Abremski.   

Abstract

The bacteriophage P1-encoded recombinase Cre forms a simple DNA-protein complex at the specific recognition site loxP. Furthermore, Cre is able to mediate a synaptic union of two loxP sites. When two loxP sites are on the same linear DNA molecule, Cre binds the two sites together to form a circular protein-DNA complex. These complexes can be resolved into a linear DNA molecule and a closed circular DNA molecule, the end products of site-specific recombination.

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Year:  1984        PMID： 6333513     DOI： 10.1016/0022-2836(84)90154-2

Source DB:  PubMed          Journal:  J Mol Biol        ISSN： 0022-2836            Impact factor:   5.469


  46 in total

1.  Validation of a self-excising marker in the human pathogen Aspergillus fumigatus by employing the beta-rec/six site-specific recombination system.

Authors:  Thomas Hartmann; Michaela Dümig; Basem M Jaber; Edyta Szewczyk; Patrick Olbermann; Joachim Morschhäuser; Sven Krappmann
Journal:  Appl Environ Microbiol       Date:  2010-07-23       Impact factor: 4.792

Review 2.  Loops in DNA: an overview of experimental and theoretical approaches.

Authors:  J-F Allemand; S Cocco; N Douarche; G Lia
Journal:  Eur Phys J E Soft Matter       Date:  2006-03-23       Impact factor: 1.890

3.  Age- and gene-dosage-dependent cre-induced abnormalities in the retinal pigment epithelium.

Authors:  Lizhi He; Mariya Marioutina; Joshua L Dunaief; Alexander G Marneros
Journal:  Am J Pathol       Date:  2014-06       Impact factor: 4.307

Review 4.  New approaches for modelling sporadic genetic disease in the mouse.

Authors:  Elizabeth M C Fisher; Eva Lana-Elola; Sheona D Watson; George Vassiliou; Victor L J Tybulewicz
Journal:  Dis Model Mech       Date:  2009 Sep-Oct       Impact factor: 5.758

5.  Heat-inducible Cre-lox system for marker excision in transgenic rice.

Authors:  Abhilasha Khattri; Soumen Nandy; Vibha Srivastava
Journal:  J Biosci       Date:  2011-03       Impact factor: 1.826

Review 6.  Investigating the genetics of visual processing, function and behaviour in zebrafish.

Authors:  Sabine L Renninger; Helia B Schonthaler; Stephan C F Neuhauss; Ralf Dahm
Journal:  Neurogenetics       Date:  2011-01-26       Impact factor: 2.660

Review 7.  Conditional gene targeting.

Authors:  K Rajewsky; H Gu; R Kühn; U A Betz; W Müller; J Roes; F Schwenk
Journal:  J Clin Invest       Date:  1996-08-01       Impact factor: 14.808

8.  Evidence for baseline retinal pigment epithelium pathology in the Trp1-Cre mouse.

Authors:  Aristomenis Thanos; Yuki Morizane; Yusuke Murakami; Andrea Giani; Dimosthenis Mantopoulos; Maki Kayama; Mi In Roh; Norman Michaud; Basil Pawlyk; Michael Sandberg; Lucy H Young; Joan W Miller; Demetrios G Vavvas
Journal:  Am J Pathol       Date:  2012-03-17       Impact factor: 4.307

9.  Single-molecule microscopy of Cre recombination.

Authors:  Jeffrey P Mumm
Journal:  Proc Natl Acad Sci U S A       Date:  2012-11-30       Impact factor: 11.205

10.  A universal vector concept for a direct genotyping of transgenic organisms and a systematic creation of homozygous lines.

Authors:  Frederic Strobl; Anita Anderl; Ernst Hk Stelzer
Journal:  Elife       Date:  2018-03-15       Impact factor: 8.140
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