| Literature DB >> 8499653 |
C Vassort1, M Rivière, G Bruneau, F Gros, J Thibault, G Levan, J Szpirer, C Szpirer.
Abstract
By use of rat cDNA probes and a panel of cell hybrids segregating rat chromosomes, the genes encoding three pyridoxal 5'-phosphate (PLP)-dependent decarboxylases--namely, DOPA-decarboxylase (Ddc), glutamic acid decarboxylase 1 and 2 (Gad1 and Gad2)--were assigned to rat Chromosomes (Chrs) 14, 3, and 17, respectively. If one takes into account chromosome localizations in the human and the mouse, the present results (i) show that a synteny group is retained on rat Chr 14, human Chr 7, and mouse Chr 11 (Ddc); (ii) strengthen the homology relation known between rat Chr 3 and human and mouse Chrs 2 (Gad1); (iii) suggest that rat Chr 17 has no extensive homology to any human chromosome; and (iv) suggest the order (Prl, Fdp)--Tpl2--Gad2 on the rat Chr 17.Entities:
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Year: 1993 PMID: 8499653 DOI: 10.1007/BF00417563
Source DB: PubMed Journal: Mamm Genome ISSN: 0938-8990 Impact factor: 2.957