Literature DB >> 2590185

Isolation and characterization of a cDNA clone encoding human aromatic L-amino acid decarboxylase.

H Ichinose1, Y Kurosawa, K Titani, K Fujita, T Nagatsu.   

Abstract

The nucleotide sequence of a cDNA clone that includes the entire coding region of human aromatic L-amino acid decarboxylase gene is presented. A human pheochromocytoma cDNA library was screened using an oligonucleotide probe which corresponded to a partial amino acid sequence of the enzyme purified from the human pheochromocytoma. The isolated cDNA clone encoded a protein of 480 amino acids with a calculated molecular mass of 53.9 kDa. The amino acid sequence Asn-Phe-Asn-Pro-His-Lys-Trp around a possible cofactor (pyridoxal phosphate) binding site is identical in human, Drosophila, and pig enzymes.

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Year:  1989        PMID： 2590185     DOI： 10.1016/0006-291x(89)91772-5

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  20 in total

1.  L-Dopa decarboxylase expression profile in human cancer cells.

Authors:  Ioanna Chalatsa; Eleftheria Nikolouzou; Emmanuel G Fragoulis; Dido Vassilacopoulou
Journal:  Mol Biol Rep       Date:  2010-06-11       Impact factor: 2.316

2.  Different mRNAs code for dopa decarboxylase in tissues of neuronal and nonneuronal origin.

Authors:  M Krieger; F Coge; F Gros; J Thibault
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-15       Impact factor: 11.205

3.  Cloning and expression of pig kidney dopa decarboxylase: comparison of the naturally occurring and recombinant enzymes.

Authors:  P S Moore; P Dominici; C Borri Voltattorni
Journal:  Biochem J       Date:  1996-04-01       Impact factor: 3.857

4.  Mutation of cysteine 111 in Dopa decarboxylase leads to active site perturbation.

Authors:  P Dominici; P S Moore; S Castellani; M Bertoldi; C B Voltattorni
Journal:  Protein Sci       Date:  1997-09       Impact factor: 6.725

5.  Molecular analysis of two genes between let-653 and let-56 in the unc-22(IV) region of Caenorhabditis elegans.

Authors:  M A Marra; S S Prasad; D L Baillie
Journal:  Mol Gen Genet       Date:  1993-01

6.  Assignment of the rat genes coding for dopa decarboxylase (DDC) and glutamic acid decarboxylases (GAD1 and GAD2).

Authors:  C Vassort; M Rivière; G Bruneau; F Gros; J Thibault; G Levan; J Szpirer; C Szpirer
Journal:  Mamm Genome       Date:  1993       Impact factor: 2.957

7.  Isolation and identification of L-dopa decarboxylase as a protein that binds to and enhances transcriptional activity of the androgen receptor using the repressed transactivator yeast two-hybrid system.

Authors:  Latif A Wafa; Helen Cheng; Mira A Rao; Colleen C Nelson; Michael Cox; Martin Hirst; Ivan Sadowski; Paul S Rennie
Journal:  Biochem J       Date:  2003-10-15       Impact factor: 3.857

8.  Quantitative expression analysis and prognostic significance of L-DOPA decarboxylase in colorectal adenocarcinoma.

Authors:  C K Kontos; I N Papadopoulos; E G Fragoulis; A Scorilas
Journal:  Br J Cancer       Date:  2010-04-27       Impact factor: 7.640

Review 9.  Tyrosine hydroxylase (TH), its cofactor tetrahydrobiopterin (BH4), other catecholamine-related enzymes, and their human genes in relation to the drug and gene therapies of Parkinson's disease (PD): historical overview and future prospects.

Authors:  Toshiharu Nagatsu; Ikuko Nagatsu
Journal:  J Neural Transm (Vienna)       Date:  2016-08-04       Impact factor: 3.575

10.  Genomic organization of the rat aromatic L-amino acid decarboxylase (AADC) locus: partial analysis reveals divergence from the Drosophila dopa decarboxylase (DDC) gene structure.

Authors:  S L Hahn; M Hahn; T H Joh
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957
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