| Literature DB >> 2591968 |
G M Lathrop1, P O'Connell, M Leppert, Y Nakamura, M Farrall, L C Tsui, J M Lalouel, R White.
Abstract
We have constructed a primary genetic linkage map from DNA markers that define 25 loci on chromosome 7. The markers form a continuous linkage group of 141 cM in males and 340 cM in females; female genetic distances were on average more than twofold higher than those in males throughout the chromosome. The average heterozygosity of the loci was 45%. A subset of the markers can be used for efficient application of this map to studies of human genetic disease.Entities:
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Year: 1989 PMID: 2591968 DOI: 10.1016/0888-7543(89)90128-6
Source DB: PubMed Journal: Genomics ISSN: 0888-7543 Impact factor: 5.736