Literature DB >> 8485813

Alkylphosphocholines: a new class of membrane-active anticancer agents.

P Hilgard1, T Klenner, J Stekar, C Unger.   

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Year:  1993        PMID: 8485813     DOI: 10.1007/bf00685608

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN: 0344-5704            Impact factor:   3.333


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  20 in total

1.  Experimental therapeutic studies with miltefosine in rats and mice.

Authors:  P Hilgard; J Stekar; R Voegeli; J H Harleman
Journal:  Prog Exp Tumor Res       Date:  1992

2.  Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin.

Authors:  I Lassing; U Lindberg
Journal:  Nature       Date:  1985 Apr 4-10       Impact factor: 49.962

3.  The specific inhibitor of protein kinase C, 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (H7), induces morphological change and cell differentiation of human neural crest-derived cell lineages.

Authors:  M T Parodi; L Varesio; G P Tonini
Journal:  FEBS Lett       Date:  1990-08-20       Impact factor: 4.124

4.  Effects of antineoplastic phospholipids on parameters of cell differentiation in U937 cells.

Authors:  C Hochhuth; D Berkovic; H Eibl; C Unger; D Doenecke
Journal:  J Cancer Res Clin Oncol       Date:  1990       Impact factor: 4.553

5.  Inhibition of protein kinase C induces differentiation in Neuro-2a cells.

Authors:  M D Miñana; V Felipo; S Grisolía
Journal:  Proc Natl Acad Sci U S A       Date:  1990-06       Impact factor: 11.205

6.  Hexadecylphosphocholine: determination of serum concentrations in rats.

Authors:  C Unger; E Fleer; W Damenz; P Hilgard; G Nagel; H Eibl
Journal:  J Lipid Mediat       Date:  1991 Jan-Feb

7.  Hexadecylphosphocholine stimulates the colony-stimulating factor-dependent growth of hemopoietic progenitor cells.

Authors:  K Vehmeyer; H Eibl; C Unger
Journal:  Exp Hematol       Date:  1992-01       Impact factor: 3.084

8.  Alkyl phosphocholines: toxicity and anticancer properties.

Authors:  C Muschiol; M R Berger; B Schuler; H R Scherf; F T Garzon; W J Zeller; C Unger; H J Eibl; D Schmähl
Journal:  Lipids       Date:  1987-11       Impact factor: 1.880

9.  Characterization of the antitumor activity of hexadecylphosphocholine (D 18506).

Authors:  P Hilgard; J Stekar; R Voegeli; J Engel; W Schumacher; H Eibl; C Unger; M R Berger
Journal:  Eur J Cancer Clin Oncol       Date:  1988-09

10.  Hexadecylphosphocholine inhibits translocation of CTP:choline-phosphate cytidylyltransferase in Madin-Darby canine kidney cells.

Authors:  C C Geilen; T Wieder; W Reutter
Journal:  J Biol Chem       Date:  1992-04-05       Impact factor: 5.157

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  17 in total

1.  Proinflammatory and cytotoxic effects of hexadecylphosphocholine (miltefosine) against drug-resistant strains of Trypanosoma cruzi.

Authors:  Victor B Saraiva; Daniel Gibaldi; José O Previato; Lucia Mendonça-Previato; Marcelo T Bozza; Célio G Freire-De-Lima; Norton Heise
Journal:  Antimicrob Agents Chemother       Date:  2002-11       Impact factor: 5.191

2.  Tumor and normal tissue pharmacokinetics of perifosine, an oral anti-cancer alkylphospholipid.

Authors:  Stefan R Vink; Jan H M Schellens; Wim J van Blitterswijk; Marcel Verheij
Journal:  Invest New Drugs       Date:  2005-08       Impact factor: 3.850

3.  Perifosine , an oral, anti-cancer agent and inhibitor of the Akt pathway: mechanistic actions, pharmacodynamics, pharmacokinetics, and clinical activity.

Authors:  Paul G Richardson; Cathy Eng; Jill Kolesar; Teru Hideshima; Kenneth C Anderson
Journal:  Expert Opin Drug Metab Toxicol       Date:  2012-05       Impact factor: 4.481

4.  Possible mechanism of miltefosine-mediated death of Leishmania donovani.

Authors:  Navin K Verma; Chinmoy S Dey
Journal:  Antimicrob Agents Chemother       Date:  2004-08       Impact factor: 5.191

5.  Evaluation of the effect of miltefosine on Trichomonas vaginalis.

Authors:  Débora Afonso Silva Rocha; Ivone de Andrade Rosa; Wanderley de Souza; Marlene Benchimol
Journal:  Parasitol Res       Date:  2013-12-22       Impact factor: 2.289

6.  Antineoplastic activity and tolerability of a novel heterocyclic alkylphospholipid, D-20133.

Authors:  J Stekar; P Hilgard; R Voegeli; H R Maurer; J Engel; B Kutscher; G Nössner; W Schumacher
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333

7.  The effect of hexadecylphosphocholine on the degradation of mitochondrial phospholipids.

Authors:  O Vagina; F N Gellerich; R Ulbrich-Hofmann
Journal:  Mol Cell Biochem       Date:  1998-06       Impact factor: 3.396

Review 8.  Current concepts of treatment in medical oncology: new anticancer drugs.

Authors:  C Unger
Journal:  J Cancer Res Clin Oncol       Date:  1996       Impact factor: 4.553

9.  Alkylphosphocholine-induced production of nitric oxide and tumor necrosis factor alpha by U 937 cells.

Authors:  I Eue; R Zeisig; D Arndt
Journal:  J Cancer Res Clin Oncol       Date:  1995       Impact factor: 4.553

10.  Effects of hexadecylphosphocholine on fatty acid metabolism: relation to cytotoxicity.

Authors:  M Goppelt-Struebe; I Winter
Journal:  Cancer Chemother Pharmacol       Date:  1995       Impact factor: 3.333

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