Literature DB >> 1699946

Effects of antineoplastic phospholipids on parameters of cell differentiation in U937 cells.

C Hochhuth1, D Berkovic, H Eibl, C Unger, D Doenecke.   

Abstract

The proliferation of the human promonocytic leukemia cell line U937 is inhibited by several ether lipids, ether lipid analogues and by phorbol esters. An early effect of this retardation of cell growth is the induction of a basic chromosomal protein, histone H1(0). Northern blot analysis of H1(0) mRNA levels reveals an increase of the mRNA concentration within a few hours after addition of hexadecylphosphocholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine. This early effect on the synthesis of a subtype of H1 proteins precedes the expression of several parameters of the monocytic differentiation of U937 cells.

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Year:  1990        PMID： 1699946     DOI： 10.1007/bf01612994

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN： 0171-5216            Impact factor:   4.553


  55 in total

1.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

2.  Butyrate induced accumulation of a 2.3 kb polyadenylated H1(0) histone mRNA in HeLa cells.

Authors:  H Kress; R Tönjes; D Doenecke
Journal:  Nucleic Acids Res       Date:  1986-09-25       Impact factor: 16.971

3.  Treatment with recombinant IFN-gamma decreases cell surface CD4 levels on peripheral blood monocytes and on myelomonocyte cell lines.

Authors:  C R Faltynek; L R Finch; P Miller; W R Overton
Journal:  J Immunol       Date:  1989-01-15       Impact factor: 5.422

4.  Appearance of a chromatin protein during the erythroid differentiation of Friend virus-transformed cells.

Authors:  F Keppel; B Allet; H Eisen
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

5.  Differential kinetics of histone H1(0) accumulation in neuronal and glial cells from rat cerebral cortex during postnatal development.

Authors:  B Piña; P Martínez; L Simón; P Suau
Journal:  Biochem Biophys Res Commun       Date:  1984-09-17       Impact factor: 3.575

6.  Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

Authors:  G K McMaster; G G Carmichael
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

7.  The expression of the histone H1 (0) gene in the human hepatoma cell line HepG2 is independent of the state of cell proliferation.

Authors:  C Hochhuth; D Doenecke
Journal:  Differentiation       Date:  1990-06       Impact factor: 3.880

8.  Effect of ether lipids on mouse granulocyte-macrophage progenitor cells.

Authors:  K Vehmeyer; D J Kim; G A Nagel; H Eibl; C Unger
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333

9.  Dibutyryl cyclic AMP stimulation of a monocyte-like cell line, U937: a model for monocyte chemotaxis and Fc receptor-related functions.

Authors:  B Sheth; I Dransfield; L J Partridge; M D Barker; D R Burton
Journal:  Immunology       Date:  1988-03       Impact factor: 7.397

10.  Induction of differentiation of cultured human and mouse myeloid leukemia cells by alkyl-lysophospholipids.

Authors:  Y Honma; T Kasukabe; M Hozumi; S Tsushima; H Nomura
Journal:  Cancer Res       Date:  1981-08       Impact factor: 12.701
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  9 in total

1.  [Spectrographic studies on the radioresistance of Miltex and miltefosine].

Authors:  G Bollmann; H Paukisch; E Bothe; W Strate; G Gademann
Journal:  Strahlenther Onkol       Date:  1997-04       Impact factor: 3.621

Review 2.  Alkylphosphocholines: a new class of membrane-active anticancer agents.

Authors:  P Hilgard; T Klenner; J Stekar; C Unger
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333

3.  Alkylphosphocholines: influence of structural variation on biodistribution at antineoplastically active concentrations.

Authors:  J Kötting; M R Berger; C Unger; H Eibl
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

4.  Hexadecylphosphocholine: oral treatment of visceral leishmaniasis in mice.

Authors:  A Kuhlencord; T Maniera; H Eibl; C Unger
Journal:  Antimicrob Agents Chemother       Date:  1992-08       Impact factor: 5.191

5.  Distribution of hexadecylphosphocholine and octadecyl-methyl-glycero-3-phosphocholine in rat tissues during steady-state treatment.

Authors:  N Marschner; J Kötting; H Eibl; C Unger
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

6.  Antitumour activity of miltefosine alone and after combination with platinum complexes on MXT mouse mammary carcinoma models.

Authors:  T Spruss; G Bernhardt; H Schönenberger; J Engel
Journal:  J Cancer Res Clin Oncol       Date:  1993       Impact factor: 4.553

7.  Investigations on the cellular uptake of hexadecylphosphocholine.

Authors:  E A Fleer; D Berkovic; H Eibl; C Unger
Journal:  Lipids       Date:  1993-08       Impact factor: 1.880

8.  Assessment of antineoplastic agents by MTT assay: partial underestimation of antiproliferative properties.

Authors:  S B Sobottka; M R Berger
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

9.  Alkylphosphocholine-induced production of nitric oxide and tumor necrosis factor alpha by U 937 cells.

Authors:  I Eue; R Zeisig; D Arndt
Journal:  J Cancer Res Clin Oncol       Date:  1995       Impact factor: 4.553
  9 in total

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