Literature DB >> 8251042

Benzo-gamma-pyrone analogues of geiparvarin: synthesis and biological evaluation against B16 melanoma cells.

P Valenti1, P Da Re, A Rampa, P Montanari, M Carrara, L Cima.   

Abstract

Chromone, flavone and xanthone analogues of geiparvarin (1) are described. Compounds 2a and 2b are more active in inhibiting the proliferation of F10 metastatic murine melanoma cells. In particular, 2a is 13 times more active at microM concentration after 48 h exposure.

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Year:  1993        PMID： 8251042

Source DB:  PubMed          Journal:  Anticancer Drug Des        ISSN： 0266-9536


  16 in total

1.  5-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetra-hydropyrimidin-5-yl)-1,3-dimethyl-1H-chromeno[2,3-d]pyrim-idine-2,4(3H,5H)-dione 3.5-hydrate.

Authors:  Subhadip Roy; Subrata Das
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-05-25

2.  6a-Nitro-6-phenyl-6,6a,6b,7,8,9,10,12a-octa-hydro-spiro-[chromeno[3,4-a]indol-izine-12,3'-indolin]-2'-one.

Authors:  Seenivasan Karthiga Devi; Thothadri Srinivasan; Jonnalagadda Naga Siva Rao; Raghavachary Raghunathan; Devadasan Velmurugan
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-05-31

3.  5-Hydr-oxy-7-meth-oxy-4H-chromen-4-one.

Authors:  Iván Brito; Jorge Bórquez; Luis Alberto Loyola; Matías López-Rodríguez
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2007-12-18

4.  2-(4-Chloro-phen-yl)-6-meth-oxy-chroman-4-one.

Authors:  Jerry P Jasinski; Albert E Pek; B Narayana; H S Yathirajan; Prakash S Nayak
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-09-11

5.  6,8-Dichloro-N-methyl-3-nitro-4-nitro-methyl-4H-chromen-2-amine.

Authors:  J Muthukumaran; A Parthiban; M Kannan; H Surya Prakash Rao; R Krishna
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-03-15

6.  (6bS*,14R*,14aR*)-Methyl 14-(4-methyl-phen-yl)-7-oxo-6b,6c,7,12b,14,14a-hexa-hydro-1H-pyrano[3,2-c:5,4-c']dichromene-14a-carboxyl-ate.

Authors:  R Ponnusamy; V Sabari; G Sivakumar; M Bakthadoss; S Aravindhan
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-01-19

7.  rac-Ethyl 2-hy-droxy-2,7,7-trimethyl-4-(4-nitro-phen-yl)-5-oxo-3,4,5,6,7,8-hexa-hydro-2H-chromene-3-carboxyl-ate.

Authors:  Abel M Maharramov; Arif I Ismiev; Bahruz A Rashidov; Rizvan K Askerov; Konstantin A Potekhin
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-12-15

8.  8-Bromo-3-phenyl-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole-3a-carbo-nitrile.

Authors:  G Suresh; J Srinivasan; M Bakthadoss; S Aravindhan
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-01-31

9.  Methyl 11,14,16-triphenyl-8,12-dioxa-14,15-di-aza-tetra-cyclo-[8.7.0.0(2,7).0(13,17)]hepta-deca-2(7),3,5,13(17),15-penta-ene-10-carboxyl-ate.

Authors:  J Kanchanadevi; G Anbalagan; D Kannan; B Gunasekaran; V Manivannan; N Bakthadoss
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-06-08

10.  3-(2-Methyl-phen-yl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole-3a-carbo-nitrile.

Authors:  G Suresh; J Srinivasan; M Bakthadoss; S Aravindhan
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-01-04
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