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Literature DB >> 8110296

Optimum use of a spacer device.

P W Barry¹, C F Robertson, C O'Callaghan.

Abstract

Nedocromil sodium given by the Fisonair spacer should be inhaled immediately. Multiple actuations into the spacer should be avoided. Delay of 20 seconds before sampling reduced the amount of drug available for inhalation in the respirable range by 81%. Placing two actuations into the spacer reduced the amount of drug available by 47%.

Entities: Chemical

Mesh：

Substances：

Year: 1993 PMID： 8110296 PMCID： PMC1029658 DOI： 10.1136/adc.69.6.693

Source DB: PubMed Journal: Arch Dis Child ISSN： 0003-9888 Impact factor: 3.791

6 in total

1. Large volume plastic spacers in asthma.

Authors: D Keeley
Journal: BMJ Date: 1992-09-12

2. Drug delivery from holding chambers with attached facemask.

Authors: M L Everard; A R Clark; A D Milner
Journal: Arch Dis Child Date: 1992-05 Impact factor: 3.791

3. The use of reservoir devices for the simultaneous delivery of two metered-dose aerosols.

Authors: A R Clark; G Rachelefsky; P L Mason; M J Goldenhersh; A Hollingworth
Journal: J Allergy Clin Immunol Date: 1990-01 Impact factor: 10.793

4. Improvement in sodium cromoglycate delivery from a spacer device by use of an antistatic lining, immediate inhalation, and avoiding multiple actuations of drug.

Authors: C O'Callaghan; J Lynch; M Cant; C Robertson
Journal: Thorax Date: 1993-06 Impact factor: 9.139

5. Improvement of pressurised aerosol deposition with Nebuhaler spacer device.

Authors: S P Newman; A B Millar; T R Lennard-Jones; F Morén; S W Clarke
Journal: Thorax Date: 1984-12 Impact factor: 9.139

6. Double blind, placebo controlled study of nedocromil sodium in asthma.

Authors: L Armenio; G Baldini; M Bardare; A Boner; R Burgio; G Cavagni; M La Rosa; F Marcucci; M Miraglia del Giudice; M R Pulejo
Journal: Arch Dis Child Date: 1993-02 Impact factor: 3.791

6 in total

9 in total

Review 1. The economic aspects of drug delivery in asthma.

Authors: R J Massie; C M Mellis
Journal: Pharmacoeconomics Date: 1997-05 Impact factor: 4.981

Review 2. Nebuliser therapy in childhood.

Authors: P W Barry; C O'Callaghan
Journal: Thorax Date: 1997-04 Impact factor: 9.139

3. Early use of inhaled nedocromil sodium in children following an acute episode of asthma.

Authors: A M Edwards; J Lyons; E Weinberg; F Weinberg; J D Gillies; G Reid; C F Robertson; P Robinson; M Dalton; P Van Asperen; C Wilson; J Mullineux; A Mullineux; P D Sly; M Cox; A F Isles
Journal: Thorax Date: 1999-04 Impact factor: 9.139

4. The effect of delay, multiple actuations and spacer static charge on the in vitro delivery of budesonide from the Nebuhaler.

Authors: P W Barry; C O'Callaghan
Journal: Br J Clin Pharmacol Date: 1995-07 Impact factor: 4.335

5. A comparative analysis of the particle size output of beclomethasone diproprionate, salmeterol xinafoate and fluticasone propionate metered dose inhalers used with the Babyhaler, Volumatic and Aerochamber spacer devices.

Authors: P W Barry; C O'callaghan
Journal: Br J Clin Pharmacol Date: 1999-04 Impact factor: 4.335

9. Usefulness of Nonvalved Spacers for Administration of Inhaled Steroids in Young Children with Recurrent Wheezing and Risk Factors for Asthma.

Authors: Carlos Kofman; Alejandro Teper
Journal: Can Respir J Date: 2018-09-03 Impact factor: 2.409