Literature DB >> 8108424

Disomic locus content mapping.

N E Morton1.   

Abstract

A linear genetic map may be constructed from segregation of markers in DNA fragments broken by radiation or shearing and/or incorporated into a vector: this is locus content mapping. Theory for monosomic locus content mapping is extended to disomy, making the phase of heterozygous markers informative for linkage and each clone potentially informative for every chromosome. Because there is no interference among breaks and phase may be reliable inferred for all heterozygous loci, multiple pairwise mapping is especially appropriate.

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Year:  1994        PMID： 8108424      PMCID： PMC43170          DOI： 10.1073/pnas.91.4.1421

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  6 in total

1.  Algorithms for a location database.

Authors:  N E Morton; A Collins; S Lawrence; D C Shields
Journal:  Ann Hum Genet       Date:  1992-07       Impact factor: 1.670

2.  Gene maps and location databases.

Authors:  N E Morton
Journal:  Ann Hum Genet       Date:  1991-07       Impact factor: 1.670

3.  Radiation hybrid mapping.

Authors:  S Lawrence; N E Morton; D R Cox
Journal:  Proc Natl Acad Sci U S A       Date:  1991-09-01       Impact factor: 11.205

4.  MAP, an expert system for multiple pairwise linkage analysis.

Authors:  N E Morton; V Andrews
Journal:  Ann Hum Genet       Date:  1989-07       Impact factor: 1.670

5.  Happy mapping: linkage mapping using a physical analogue of meiosis.

Authors:  P H Dear; P R Cook
Journal:  Nucleic Acids Res       Date:  1993-01-11       Impact factor: 16.971

6.  Radiation hybrid mapping: a somatic cell genetic method for constructing high-resolution maps of mammalian chromosomes.

Authors:  D R Cox; M Burmeister; E R Price; S Kim; R M Myers
Journal:  Science       Date:  1990-10-12       Impact factor: 47.728
  6 in total
  1 in total

1.  Studies on locus content mapping.

Authors:  J W Teague; A Collins; N E Morton
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-15       Impact factor: 11.205
  1 in total

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