Literature DB >> 2596832

MAP, an expert system for multiple pairwise linkage analysis.

N E Morton1, V Andrews.   

Abstract

The logic of a program for multiple pairwise linkage analysis under interference is set forth, including a seriation algorithm to obtain a trial order, a mapping bootstrap to improve the trial order, and three procedures for quality control to detect mistyping. This approach is compared with multipoint analysis under null interference, which substantially overestimates map length and cannot incorporate a variety of data.

Mesh：

Year:  1989        PMID： 2596832     DOI： 10.1111/j.1469-1809.1989.tb01793.x

Source DB:  PubMed          Journal:  Ann Hum Genet        ISSN： 0003-4800            Impact factor:   1.670


  22 in total

1.  Linkage analysis in the presence of errors I: complex-valued recombination fractions and complex phenotypes.

Authors:  H H Göring; J D Terwilliger
Journal:  Am J Hum Genet       Date:  2000-03       Impact factor: 11.025

2.  Obligate short-arm exchange in de novo Robertsonian translocation formation influences placement of crossovers in chromosome 21 nondisjunction.

Authors:  Sue Ann Berend; Scott L Page; William Atkinson; Christopher McCaskill; Neil E Lamb; Stephanie L Sherman; Lisa G Shaffer
Journal:  Am J Hum Genet       Date:  2002-12-23       Impact factor: 11.025

3.  Linkage analysis in the presence of errors II: marker-locus genotyping errors modeled with hypercomplex recombination fractions.

Authors:  H H Göring; J D Terwilliger
Journal:  Am J Hum Genet       Date:  2000-03       Impact factor: 11.025

4.  Integration of gene maps: chromosome 1.

Authors:  A Collins; B J Keats; N Dracopoli; D C Shields; N E Morton
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-15       Impact factor: 11.205

5.  Construction of a map of chromosome 16 by using radiation hybrids.

Authors:  I Ceccherini; G Romeo; S Lawrence; M H Breuning; P C Harris; H Himmelbauer; A M Frischauf; G R Sutherland; G G Germino; S T Reeders
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-01       Impact factor: 11.205

6.  Trisomy 21: association between reduced recombination and nondisjunction.

Authors:  S L Sherman; N Takaesu; S B Freeman; M Grantham; C Phillips; R D Blackston; P A Jacobs; A E Cockwell; V Freeman; I Uchida
Journal:  Am J Hum Genet       Date:  1991-09       Impact factor: 11.025

7.  Influence of aberrant observations on high-resolution linkage analysis outcomes.

Authors:  K H Buetow
Journal:  Am J Hum Genet       Date:  1991-11       Impact factor: 11.025

8.  Error filtration, interference, and the human linkage map.

Authors:  D C Shields; A Collins; K H Buetow; N E Morton
Journal:  Proc Natl Acad Sci U S A       Date:  1991-08-01       Impact factor: 11.205

9.  XY chromosome nondisjunction in man is associated with diminished recombination in the pseudoautosomal region.

Authors:  T J Hassold; S L Sherman; D Pettay; D C Page; P A Jacobs
Journal:  Am J Hum Genet       Date:  1991-08       Impact factor: 11.025

10.  Radiation hybrid mapping.

Authors:  S Lawrence; N E Morton; D R Cox
Journal:  Proc Natl Acad Sci U S A       Date:  1991-09-01       Impact factor: 11.205
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