| Literature DB >> 8086829 |
A M Witteman1, J H Akkerdaas, J van Leeuwen, J S van der Zee, R C Aalberse.
Abstract
A monoclonal antibody to Dermatophagoides pteronyssinus is described that cross-reacts with an IgE-binding antigen present in insects, Crustacea (e.g. shrimp) and other invertebrates. By means of sodium dodecyl sulfate-polyacrylamide gel electrophoresis, gel filtration and immunofluorescence it was shown that this monoclonal antibody presumably recognizes tropomyosin. Tropomyosin was shown to be involved in cross-reactivity between mite, shrimp and insects in shrimp-allergic patients.Entities:
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Year: 1994 PMID： 8086829 DOI： 10.1159/000236803
Source DB: PubMed Journal: Int Arch Allergy Immunol ISSN： 1018-2438 Impact factor: 2.749