Riccardo Asero1, Valerio Pravettoni2, Enrico Scala3, Danilo Villalta4. 1. Ambulatorio di Allergologia, Clinica San Carlo, Via Ospedale 21, 20037, Paderno Dugnano (MI), Italy. r.asero@libero.it. 2. Department of General Medicine, Immunology and Allergy, IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, Via Sforza 35, 20122, Milan, Italy. 3. Allergy Unit, Istituto Dermopatico dell'Immacolata, Rome, Italy. 4. Immunologia e Allergologia, P.O. Santa Maria degli Angeli, Pordenone, Italy.
Abstract
PURPOSE OF REVIEW: Focusing on the strict relationship between house dust mites and crustaceans from the allergenic point of view. RECENT FINDINGS: The well-known tropomyosin was considered for years as the cross-reacting allergen between shrimp and house dust mites. In the last few years, several allergens not only in shrimps but also in house dust mite have been identified and other molecules other than tropomyosin have been shown to cross-react between crustaceans and mites. The present review investigates the very complex allergen sources in shrimp and mites, giving a satisfactorily complete picture of the interrelationships between common allergens. Several minor HDM allergens are homologous to major and minor shrimp allergens; tropomyosin is not the only cross-reactive allergen between shrimp and mites.
PURPOSE OF REVIEW: Focusing on the strict relationship between house dust mites and crustaceans from the allergenic point of view. RECENT FINDINGS: The well-known tropomyosin was considered for years as the cross-reacting allergen between shrimp and house dust mites. In the last few years, several allergens not only in shrimps but also in house dust mite have been identified and other molecules other than tropomyosin have been shown to cross-react between crustaceans and mites. The present review investigates the very complex allergen sources in shrimp and mites, giving a satisfactorily complete picture of the interrelationships between common allergens. Several minor HDM allergens are homologous to major and minor shrimp allergens; tropomyosin is not the only cross-reactive allergen between shrimp and mites.
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