Literature DB >> 8002387

Pyrroindomycins, novel antibiotics produced by Streptomyces rugosporus sp. LL-42D005. I. Isolation and structure determination.

W Ding1, D R Williams, P Northcote, M M Siegel, R Tsao, J Ashcroft, G O Morton, M Alluri, D Abbanat, W M Maiese.   

Abstract

Pyrroindomycins A and B were isolated from fermentations of culture LL-42D005, a strain of Streptomyces rugosporus. Pyrroindomycins possess potent antimicrobial activities against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci. Their structures have been determined by using 1- and 2-D NMR, mass spectroscopy and chemical degradations. Pyrroindomycins are the first natural products that contain the highly unsaturated pyrroloindole moiety.

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Year:  1994        PMID： 8002387     DOI： 10.7164/antibiotics.47.1250

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  13 in total

Review 1.  Natural [4 + 2]-Cyclases.

Authors:  Byung-Sun Jeon; Shao-An Wang; Mark W Ruszczycky; Hung-Wen Liu
Journal:  Chem Rev       Date:  2016-12-01       Impact factor: 60.622

Review 2.  Recent advances of Diels-Alderases involved in natural product biosynthesis.

Authors:  Atsushi Minami; Hideaki Oikawa
Journal:  J Antibiot (Tokyo)       Date:  2016-06-15       Impact factor: 2.649

3.  An enzymatic [4+2] cyclization cascade creates the pentacyclic core of pyrroindomycins.

Authors:  Zhenhua Tian; Peng Sun; Yan Yan; Zhuhua Wu; Qingfei Zheng; Shuaixiang Zhou; Hua Zhang; Futao Yu; Xinying Jia; Dandan Chen; Attila Mándi; Tibor Kurtán; Wen Liu
Journal:  Nat Chem Biol       Date:  2015-03-02       Impact factor: 15.040

Review 4.  Astonishing diversity of natural surfactants: 6. Biologically active marine and terrestrial alkaloid glycosides.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2005-11       Impact factor: 1.880

5.  Bi- and Tetracyclic Spirotetronates from the Coal Mine Fire Isolate Streptomyces sp. LC-6-2.

Authors:  Xiachang Wang; Sherif I Elshahawi; Wenlong Cai; Yinan Zhang; Larissa V Ponomareva; Xiabin Chen; Gregory C Copley; James C Hower; Chang-Guo Zhan; Sean Parkin; Jürgen Rohr; Steven G Van Lanen; Khaled A Shaaban; Jon S Thorson
Journal:  J Nat Prod       Date:  2017-03-30       Impact factor: 4.050

6.  Natural Diels-Alderases: Elusive and Irresistable.

Authors:  Kimberly Klas; Sachiko Tsukamoto; David H Sherman; Robert M Williams
Journal:  J Org Chem       Date:  2015-12-04       Impact factor: 4.354

7.  The second enzyme in pyrrolnitrin biosynthetic pathway is related to the heme-dependent dioxygenase superfamily.

Authors:  Walter De Laurentis; Leang Khim; J L Ross Anderson; Ariane Adam; Kenneth A Johnson; Robert S Phillips; Stephen K Chapman; Karl-Heinz van Pee; James H Naismith
Journal:  Biochemistry       Date:  2007-10-09       Impact factor: 3.162

8.  4-Phenyl-sulfon-yl-2-(p-tolyl-sulfon-yl)-1H,8H-pyrrolo-[2,3-b]indole.

Authors:  Jeanese C Badenock; Jason A Jordan; Erin T Pelkey; Gordon W Gribble; Jerry P Jasinski
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-10-09

9.  Computational Investigation of the Mechanism of Diels-Alderase PyrI4.

Authors:  Yike Zou; Song Yang; Jacob N Sanders; Wei Li; Peiyuan Yu; Hongbo Wang; Zhijun Tang; Wen Liu; K N Houk
Journal:  J Am Chem Soc       Date:  2020-11-14       Impact factor: 16.383

10.  The crystal structure of AbsH3: A putative flavin adenine dinucleotide-dependent reductase in the abyssomicin biosynthesis pathway.

Authors:  Jonathan A Clinger; Xiachang Wang; Wenlong Cai; Yanyan Zhu; Mitchell D Miller; Chang-Guo Zhan; Steven G Van Lanen; Jon S Thorson; George N Phillips
Journal:  Proteins       Date:  2020-10-21
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