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Literature DB >> 79181

Somatic cell hybrids producing antibodies specific for the tumor antigen of simian virus 40.

Abstract

We have produced somatic cell hybrids between mouse myeloma cells deficient in hypoxanthine phosphoribosyltransferase IMP: pyrophosphate phosphoribosyltransferase; EC 2.4.2.8) and spleen cells derived from mice primed with either syngeneic or allogeneic cells transformed by simian virus 40. Such hybrids produced antibodies specific for simian virus 40 tumor (T) antigen. Only four of twelve independent hybrid cell cultures produced antibodies against simian virus 40 T antigen that crossreacted with the T antigen induced by BK virus, a human papovavirus isolated from patients who had undergone immunosuppressive therapy.

Entities: Disease Species

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Year: 1978 PMID： 79181 PMCID： PMC392544 DOI： 10.1073/pnas.75.5.2320

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

12 in total

1. SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS.

Authors: J W LITTLEFIELD
Journal: Science Date: 1964-08-14 Impact factor: 47.728

2. A SPECIFIC COMPLEMENT-FIXING ANTIGEN PRESENT IN SV40 TUMOR AND TRANSFORMED CELLS.

Authors: P H BLACK; W P ROWE; H C TURNER; R J HUEBNER
Journal: Proc Natl Acad Sci U S A Date: 1963-12 Impact factor: 11.205

3. Malignant transformation of hamster kidney cells by BK virus.

Authors: M Portolani; G Barbanti-Brodano; M L Placa
Journal: J Virol Date: 1975-02 Impact factor: 5.103

4. Repertoire of antiviral antibodies expressed by somatic cell hybrids.

Authors: W Gerhard; C M Croce; D Lopes; H Koprowski
Journal: Proc Natl Acad Sci U S A Date: 1978-03 Impact factor: 11.205

5. Spliced early mRNAs of simian virus 40.

Authors: A J Berk; P A Sharp
Journal: Proc Natl Acad Sci U S A Date: 1978-03 Impact factor: 11.205

6. Organization and expression of early genes of simian virus 40.

Authors: L V Crawford; C N Cole; A E Smith; E Paucha; P Tegtmeyer; K Rundell; P Berg
Journal: Proc Natl Acad Sci U S A Date: 1978-01 Impact factor: 11.205

7. New human papovavirus (B.K.) isolated from urine after renal transplantation.

Authors: S D Gardner; A M Field; D V Coleman; B Hulme
Journal: Lancet Date: 1971-06-19 Impact factor: 79.321

8. Cell-free translation of simian virus 40 early messenger RNA coding for viral T-antigen.

Authors: C Prives; E Gilboa; M Revel; E Winocour
Journal: Proc Natl Acad Sci U S A Date: 1977-02 Impact factor: 11.205

9. Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells.

Authors: H Koprowski; W Gerhard; C M Croce
Journal: Proc Natl Acad Sci U S A Date: 1977-07 Impact factor: 11.205

10. DETECTION OF SPECIFIC ANTIGEN IN SV40-TRANSFORMED CELLS BY IMMUNOFLUORESCENCE.

Authors: J H POPE; W P ROWE
Journal: J Exp Med Date: 1964-08-01 Impact factor: 14.307

18 in total

1. Transformation of human embryonic kidney cells by human papovarirus BK.

Authors: A F Purchio; G C Fareed
Journal: J Virol Date: 1979-02 Impact factor: 5.103

2. BK virus DNA sequence coding for the t and T antigens and evaluation of methods for determining sequence homology.

Authors: R C Yang; A Young; R Wu
Journal: J Virol Date: 1980-05 Impact factor: 5.103

3. Production of monoclonal antibodies against nucleocapsid proteins of herpes simplex virus types 1 and 2.

Authors: M Zweig; C J Heilman; H Rabin; R F Hopkins; R H Neubauer; B Hampar
Journal: J Virol Date: 1979-11 Impact factor: 5.103

4. Monoclonal antibodies specific for simian virus 40 tumor antigens.

Authors: E Harlow; L V Crawford; D C Pim; N M Williamson
Journal: J Virol Date: 1981-09 Impact factor: 5.103

5. Spontaneous transformation of a cloned cell line of normal diploid bovine vascular endothelial cells.

Authors: S D Gorman; E Hoffman; W W Nichols; V J Cristofalo
Journal: In Vitro Date: 1984-04

6. Cellular proteins reactive with monoclonal antibodies directed against simian virus 40 T-antigen.

Authors: L Crawford; K Leppard; D Lane; E Harlow
Journal: J Virol Date: 1982-05 Impact factor: 5.103

7. An oligomeric form of simian virus 40 large T-antigen is immunologically related to the cellular tumor antigen p53.

Authors: K N Leppard; L V Crawford
Journal: J Virol Date: 1984-05 Impact factor: 5.103

8. Antibodies specific for the carboxy- and amino-terminal regions of simian virus 40 large tumor antigen.

Authors: G Walter; K H Scheidtmann; A Carbone; A P Laudano; R F Doolittle
Journal: Proc Natl Acad Sci U S A Date: 1980-09 Impact factor: 11.205

9. DNA-transformed murine teratocarcinoma cells: regulation of expression of simian virus 40 tumor antigen in stem versus differentiated cells.

Authors: A Linnenbach; K Huebner; C M Croce
Journal: Proc Natl Acad Sci U S A Date: 1980-08 Impact factor: 11.205

10. The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene.

Authors: Eric S Martin; Rossano Cesari; Francesca Pentimalli; Kristine Yoder; Richard Fishel; Andrew L Himelstein; S Eric Martin; Andrew K Godwin; Massimo Negrini; Carlo M Croce
Journal: Proc Natl Acad Sci U S A Date: 2003-09-22 Impact factor: 11.205