Literature DB >> 7909542

Lipid synthesis in mycobacteria: characterization of the biotin carboxyl carrier protein genes from Mycobacterium leprae and M. tuberculosis.

E Norman1, K A De Smet, N G Stoker, C Ratledge, P R Wheeler, J W Dale.   

Abstract

The causative agents of leprosy and tuberculosis, Mycobacterium leprae and Mycobacterium tuberculosis, have a lipid-rich cell envelope which contributes to virulence and antibiotic resistance. Acyl coenzyme A carboxylase, which catalyzes the first committed step of lipid biosynthesis, consists in mycobacteria of two subunits, one of which is biotinylated. Genes from M. leprae and M. tuberculosis encoding a biotinylated protein have been cloned and sequenced. Analysis of the derived protein sequences demonstrated the presence of biotin-binding sites and putative ATP-bicarbonate interactions sites, consistent with the proteins having a biotin carboxylase function as well as their being biotin carrier proteins.

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Year:  1994        PMID： 7909542      PMCID： PMC205389          DOI： 10.1128/jb.176.9.2525-2531.1994

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  31 in total

1.  Nucleotide sequence of the fabE gene and flanking regions containing a bent DNA sequence of Escherichia coli.

Authors:  S Muramatsu; T Mizuno
Journal:  Nucleic Acids Res       Date:  1989-05-25       Impact factor: 16.971

2.  Biotin carboxyl carrier protein from Escherichia coli.

Authors:  R R Fall; P R Vagelos
Journal:  Methods Enzymol       Date:  1975       Impact factor: 1.600

3.  Sequence and domain structure of yeast pyruvate carboxylase.

Authors:  F Lim; C P Morris; F Occhiodoro; J C Wallace
Journal:  J Biol Chem       Date:  1988-08-15       Impact factor: 5.157

4.  Fast and sensitive multiple sequence alignments on a microcomputer.

Authors:  D G Higgins; P M Sharp
Journal:  Comput Appl Biosci       Date:  1989-04

5.  CLUSTAL: a package for performing multiple sequence alignment on a microcomputer.

Authors:  D G Higgins; P M Sharp
Journal:  Gene       Date:  1988-12-15       Impact factor: 3.688

6.  Purification and subunit structure of propionyl coenzyme A carboxylase of Mycobacterium smegmatis.

Authors:  K P Henrikson; S H Allen
Journal:  J Biol Chem       Date:  1979-07-10       Impact factor: 5.157

7.  A comprehensive set of sequence analysis programs for the VAX.

Authors:  J Devereux; P Haeberli; O Smithies
Journal:  Nucleic Acids Res       Date:  1984-01-11       Impact factor: 16.971

8.  The subunit structure and function of the propionyl coenzyme A carboxylase of Mycobacterium smegmatis.

Authors:  F C Haase; K P Henrikson; D H Treble; S H Allen
Journal:  J Biol Chem       Date:  1982-10-25       Impact factor: 5.157

9.  Genes for two subunits of acetyl coenzyme A carboxylase of Anabaena sp. strain PCC 7120: biotin carboxylase and biotin carboxyl carrier protein.

Authors:  P Gornicki; L A Scappino; R Haselkorn
Journal:  J Bacteriol       Date:  1993-08       Impact factor: 3.490

10.  Isolation and characterization of acyl coenzyme A carboxylases from Mycobacterium tuberculosis and Mycobacterium bovis, which produce multiple methyl-branched mycocerosic acids.

Authors:  D L Rainwater; P E Kolattukudy
Journal:  J Bacteriol       Date:  1982-08       Impact factor: 3.490
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  9 in total

1.  Crystallization and preliminary X-ray diffraction analysis of biotin acetyl-CoA carboxylase ligase (BirA) from Mycobacterium tuberculosis.

Authors:  Vibha Gupta; Rakesh K Gupta; Garima Khare; Avadhesha Surolia; Dinakar M Salunke; Anil K Tyagi
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2008-05-23

2.  Insights on the evolution of metabolic networks of unicellular translationally biased organisms from transcriptomic data and sequence analysis.

Authors:  Alessandra Carbone; Richard Madden
Journal:  J Mol Evol       Date:  2005-09-26       Impact factor: 2.395

3.  Molecular characterization of Lactobacillus plantarum genes for beta-ketoacyl-acyl carrier protein synthase III (fabH) and acetyl coenzyme A carboxylase (accBCDA), which are essential for fatty acid biosynthesis.

Authors:  P Kiatpapan; H Kobayashi; M Sakaguchi; H Ono; M Yamashita; Y Kaneko; Y Murooka
Journal:  Appl Environ Microbiol       Date:  2001-01       Impact factor: 4.792

4.  Biochemical and molecular biological characterization of CAC2, the Arabidopsis thaliana gene coding for the biotin carboxylase subunit of the plastidic acetyl-coenzyme A carboxylase.

Authors:  J Sun; J Ke; J L Johnson; B J Nikolau; E S Wurtele
Journal:  Plant Physiol       Date:  1997-12       Impact factor: 8.340

5.  Structure of a gene encoding a cytosolic acetyl-CoA carboxylase of hexaploid wheat.

Authors:  J Podkowinski; G E Sroga; R Haselkorn; P Gornicki
Journal:  Proc Natl Acad Sci U S A       Date:  1996-03-05       Impact factor: 11.205

6.  The genes encoding the biotin carboxyl carrier protein and biotin carboxylase subunits of Bacillus subtilis acetyl coenzyme A carboxylase, the first enzyme of fatty acid synthesis.

Authors:  P Marini; S J Li; D Gardiol; J E Cronan; D de Mendoza
Journal:  J Bacteriol       Date:  1995-12       Impact factor: 3.490

7.  Characterization of a bifunctional archaeal acyl coenzyme A carboxylase.

Authors:  Songkran Chuakrut; Hiroyuki Arai; Masaharu Ishii; Yasuo Igarashi
Journal:  J Bacteriol       Date:  2003-02       Impact factor: 3.490

8.  A chemical proteomics approach to profiling the ATP-binding proteome of Mycobacterium tuberculosis.

Authors:  Lisa M Wolfe; Usha Veeraraghavan; Susan Idicula-Thomas; Stephan Schürer; Krister Wennerberg; Robert Reynolds; Gurdyal S Besra; Karen M Dobos
Journal:  Mol Cell Proteomics       Date:  2013-03-05       Impact factor: 5.911

9.  Differential Expression of MicroRNAs in Leprosy Skin Lesions.

Authors:  Cleverson T Soares; Ana P F Trombone; Luciana R V Fachin; Patricia S Rosa; Cássio C Ghidella; Rodrigo F Ramalho; Mabel G Pinilla; Alex F Carvalho; Dirce N Carrara; Fernando A Soares; Andrea F F Belone
Journal:  Front Immunol       Date:  2017-08-25       Impact factor: 7.561
  9 in total

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