Literature DB >> 2720464

Fast and sensitive multiple sequence alignments on a microcomputer.

D G Higgins1, P M Sharp.   

Abstract

A strategy is described for the rapid alignment of many long nucleic acid or protein sequences on a microcomputer. The program described can handle up to 100 sequences of 1200 residues each. The approach is based on progressively aligning sequences according to the branching order in an initial phylogenetic tree. The results obtained using the package appear to be as sensitive as those from any other available method.

Mesh:

Year:  1989        PMID: 2720464     DOI: 10.1093/bioinformatics/5.2.151

Source DB:  PubMed          Journal:  Comput Appl Biosci        ISSN: 0266-7061


  418 in total

1.  Update of AMmtDB: a database of multi-aligned metazoa mitochondrial DNA sequences.

Authors:  C Lanave; S Liuni; F Licciulli; M Attimonelli
Journal:  Nucleic Acids Res       Date:  2000-01-01       Impact factor: 16.971

2.  Naturally occurring lactococcal plasmid pAH90 links bacteriophage resistance and mobility functions to a food-grade selectable marker.

Authors:  D O' Sullivan ; R P Ross; D P Twomey; G F Fitzgerald; C Hill; A Coffey
Journal:  Appl Environ Microbiol       Date:  2001-02       Impact factor: 4.792

3.  Cracks in the beta-can: fluorescent proteins from Anemonia sulcata (Anthozoa, Actinaria).

Authors:  J Wiedenmann; C Elke; K D Spindler; W Funke
Journal:  Proc Natl Acad Sci U S A       Date:  2000-12-19       Impact factor: 11.205

4.  Sequence and antigenic variability of the Helicobacter mustelae surface ring protein Hsr.

Authors:  N Forester; J S Lumsden; T O'Croinin; P W O'Toole
Journal:  Infect Immun       Date:  2001-05       Impact factor: 3.441

5.  ANT1, an aromatic and neutral amino acid transporter in Arabidopsis.

Authors:  L Chen; A Ortiz-Lopez; A Jung; D R Bush
Journal:  Plant Physiol       Date:  2001-04       Impact factor: 8.340

6.  Coevolution between a cockroach and its bacterial endosymbiont: a biogeographical perspective.

Authors:  J W Clark; S Hossain; C A Burnside; S Kambhampati
Journal:  Proc Biol Sci       Date:  2001-02-22       Impact factor: 5.349

7.  Refinement of modelled structures by knowledge-based energy profiles and secondary structure prediction: application to the human procarboxypeptidase A2.

Authors:  P Aloy; J M Mas; M A Martí-Renom; E Querol; F X Avilés; B Oliva
Journal:  J Comput Aided Mol Des       Date:  2000-01       Impact factor: 3.686

8.  A shift from oral to blood pH is a stimulus for adaptive gene expression of Streptococcus gordonii CH1 and induces protection against oxidative stress and enhanced bacterial growth by expression of msrA.

Authors:  A J Vriesema; J Dankert; S A Zaat
Journal:  Infect Immun       Date:  2000-03       Impact factor: 3.441

9.  A novel type of AmpC beta-lactamase, ACC-1, produced by a Klebsiella pneumoniae strain causing nosocomial pneumonia.

Authors:  A Bauernfeind; I Schneider; R Jungwirth; H Sahly; U Ullmann
Journal:  Antimicrob Agents Chemother       Date:  1999-08       Impact factor: 5.191

10.  Nonlinear methods in the analysis of protein sequences: a case study in rubredoxins.

Authors:  A Giuliani; R Benigni; P Sirabella; J P Zbilut; A Colosimo
Journal:  Biophys J       Date:  2000-01       Impact factor: 4.033

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