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Literature DB >> 7903569

Assignment of the dipeptidylpeptidase IV (DPP4) gene to pig chromosome 15q21.

P D Thomsen¹, H Qvist, L Marklund, L Andersson, H Sjöström, O Norén.

Abstract

A porcine 2-kb partial dipeptidylpeptidase IV (DPP4, EC 3.4.14.5) cDNA clone and a porcine 16-kb genomic fragment containing parts of the DPP4 gene were isolated, characterized, and used as probes to map the DPP4 gene to pig Chr (Chr) 15q21 by fluorescence in situ hybridization. A two-allele RFLP was revealed for the DPP4 gene. This polymorphism was utilized in a linkage test against the erythrocyte antigen G (EAG), previously assigned to Chr 15, and the microsatellite S0088, which is linked to EAG. The linkage analyses revealed significant evidence for linkage confirming the assignment of DPP4 to Chr 15.

Entities: Gene Species

Mesh：

Substances：

Year: 1993 PMID： 7903569 DOI： 10.1007/bf00361393

Source DB: PubMed Journal: Mamm Genome ISSN： 0938-8990 Impact factor: 2.957

24 in total

1. Assignment of a porcine male-specific DNA repeat to Y-chromosomal heterochromatin.

Authors: P D Thomsen; J Hindkjaer; K Christensen
Journal: Cytogenet Cell Genet Date: 1992

2. N-terminal amino-acid sequence of pig kidney dipeptidyl peptidase IV solubilized by autolysis.

Authors: R Seidl; K Mann; W Schäfer
Journal: Biol Chem Hoppe Seyler Date: 1991-03

3. Dipeptidyl peptidase IV, a kidney brush-border serine peptidase.

Authors: A J Kenny; A G Booth; S G George; J Ingram; D Kershaw; E J Wood; A R Young
Journal: Biochem J Date: 1976-07-01 Impact factor: 3.857

4. Multiple restriction fragment length polymorphisms in the porcine calcium release channel gene (CRC): assignment to the halothane (HAL) linkage group.

Authors: P Mariani; M Johansson; H Ellegren; I Harbitz; R K Juneja; L Andersson
Journal: Anim Genet Date: 1992 Impact factor: 3.169

5. Multilocus linkage analysis in humans: detection of linkage and estimation of recombination.

Authors: G M Lathrop; J M Lalouel; C Julier; J Ott
Journal: Am J Hum Genet Date: 1985-05 Impact factor: 11.025

6. Dipeptidyl peptidase IV (CD 26) gene expression in enterocyte-like colon cancer cell lines HT-29 and Caco-2. Cloning of the complete human coding sequence and changes of dipeptidyl peptidase IV mRNA levels during cell differentiation.

Authors: D Darmoul; M Lacasa; L Baricault; D Marguet; C Sapin; P Trotot; A Barbat; G Trugnan
Journal: J Biol Chem Date: 1992-03-05 Impact factor: 5.157

7. Localization of the pig luteinizing hormone/choriogonadotropin receptor gene (LHCGR) by radioactive and nonradioactive in situ hybridization.

Authors: M Yerle; O Galman; Y Lahbib-Mansais; J Gellin
Journal: Cytogenet Cell Genet Date: 1992

8. DNA sequencing with chain-terminating inhibitors.

Authors: F Sanger; S Nicklen; A R Coulson
Journal: Proc Natl Acad Sci U S A Date: 1977-12 Impact factor: 11.205

9. The gene for dominant white color in the pig is closely linked to ALB and PDGRFRA on chromosome 8.

Authors: M Johansson; H Ellegren; L Marklund; U Gustavsson; E Ringmar-Cederberg; K Andersson; I Edfors-Lilja; L Andersson
Journal: Genomics Date: 1992-12 Impact factor: 5.736

10. Isolation of a cDNA probe for the human intestinal dipeptidylpeptidase IV and assignment of the gene locus DPP4 to chromosome 2.

Authors: D Darmoul; M Lacasa; I Chantret; D M Swallow; G Trugnan
Journal: Ann Hum Genet Date: 1990-07 Impact factor: 1.670

6 in total

Assignment of the dipeptidylpeptidase IV (DPP4) gene to pig chromosome 15q21.

1. Assignment of a porcine male-specific DNA repeat to Y-chromosomal heterochromatin.

2. N-terminal amino-acid sequence of pig kidney dipeptidyl peptidase IV solubilized by autolysis.

3. Dipeptidyl peptidase IV, a kidney brush-border serine peptidase.

4. Multiple restriction fragment length polymorphisms in the porcine calcium release channel gene (CRC): assignment to the halothane (HAL) linkage group.

5. Multilocus linkage analysis in humans: detection of linkage and estimation of recombination.

6. Dipeptidyl peptidase IV (CD 26) gene expression in enterocyte-like colon cancer cell lines HT-29 and Caco-2. Cloning of the complete human coding sequence and changes of dipeptidyl peptidase IV mRNA levels during cell differentiation.

7. Localization of the pig luteinizing hormone/choriogonadotropin receptor gene (LHCGR) by radioactive and nonradioactive in situ hybridization.

8. DNA sequencing with chain-terminating inhibitors.

9. The gene for dominant white color in the pig is closely linked to ALB and PDGRFRA on chromosome 8.

10. Isolation of a cDNA probe for the human intestinal dipeptidylpeptidase IV and assignment of the gene locus DPP4 to chromosome 2.

1. A major locus (RN) affecting muscle glycogen content is located on pig chromosome 15.

2. Accurate mapping of the "acid meat" RN gene on genetic and physical maps of pig chromosome 15.

3. The cytogenetic map of the domestic pig.

4. Linkage maps of porcine chromosomes 3, 6, and 9 based on 31 polymorphic markers.

5. The PiGMaP consortium linkage map of the pig (Sus scrofa).

Review 6. The PiGMaP consortium cytogenetic map of the domestic pig (Sus scrofa domestica).