Literature DB >> 1354420

Multiple restriction fragment length polymorphisms in the porcine calcium release channel gene (CRC): assignment to the halothane (HAL) linkage group.

P Mariani1, M Johansson, H Ellegren, I Harbitz, R K Juneja, L Andersson.   

Abstract

Two cDNA probes for the porcine calcium release channel gene (CRC) were used in restriction fragment length polymorphism (RFLP) analysis in an attempt to develop genetic markers linked to the malignant hyperthermia (stress susceptibility) gene (HAL). Three TaqI RFLPs, denoted CRC1-CRC3, each composed of two alleles, were detected. RFLPs were also detected with MspI and PvuII, but the MspI RFLP correlated completely with CRC3 in this material and the PvuII RFLP could not be scored reliably due to a minute size difference between the two allelic fragments. The autosomal codominant inheritance of these RFLP loci was confirmed by family analyses. Significant evidence for genetic linkage between the CRC1/CRC3 loci and the A1BG locus in the HAL linkage group confirmed a previous assignment of the CRC gene to chromosome 6 in the pig.

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Year:  1992        PMID: 1354420     DOI: 10.1111/j.1365-2052.1992.tb00138.x

Source DB:  PubMed          Journal:  Anim Genet        ISSN: 0268-9146            Impact factor:   3.169


  9 in total

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Authors:  M Johansson; H Ellegren; L Marklund; W Coppieters; L Andersson
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6.  Assignment of the dipeptidylpeptidase IV (DPP4) gene to pig chromosome 15q21.

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Authors:  G H Gudmundsson; K P Magnusson; B P Chowdhary; M Johansson; L Andersson; H G Boman
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Authors:  A L Archibald; C S Haley; J F Brown; S Couperwhite; H A McQueen; D Nicholson; W Coppieters; A Van de Weghe; A Stratil; A K Winterø
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9.  Limited polymorphism at major histocompatibility complex (MHC) loci in the Swedish moose A. alces.

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