Literature DB >> 7861404

Inhibitors of HIV-1 protease containing the novel and potent (R)-(hydroxyethyl)sulfonamide isostere.

M L Vazquez1, M L Bryant, M Clare, G A DeCrescenzo, E M Doherty, J N Freskos, D P Getman, K A Houseman, J A Julien, G P Kocan.   

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Year:  1995        PMID： 7861404     DOI： 10.1021/jm00004a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  6 in total

1.  Asymmetric Aldol Route to Hydroxyethylamine Isostere: Stereoselective Synthesis of the Core Unit of Saquinavir.

Authors:  Arun K Ghosh; Khaja Azhar Hussain; Steve Fidanze
Journal:  J Org Chem       Date:  1997-08-22       Impact factor: 4.354

2.  cis-1-Aminoindan-2-ol in Asymmetric Syntheses.

Authors:  Arun K Ghosh; Steve Fidanze; Chris H Senanayake
Journal:  Synthesis (Stuttg)       Date:  1998-07       Impact factor: 3.157

3.  Calculation of solvation and binding free energy differences between VX-478 and its analogs by free energy perturbation and AMSOL methods.

Authors:  B G Rao; E E Kim; M A Murcko
Journal:  J Comput Aided Mol Des       Date:  1996-02       Impact factor: 3.686

Review 4.  Harnessing nature's insight: design of aspartyl protease inhibitors from treatment of drug-resistant HIV to Alzheimer's disease.

Authors:  Arun K Ghosh
Journal:  J Med Chem       Date:  2009-04-23       Impact factor: 7.446

Review 5.  Organic carbamates in drug design and medicinal chemistry.

Authors:  Arun K Ghosh; Margherita Brindisi
Journal:  J Med Chem       Date:  2015-01-07       Impact factor: 7.446

Review 6.  Enhancing protein backbone binding--a fruitful concept for combating drug-resistant HIV.

Authors:  Arun K Ghosh; David D Anderson; Irene T Weber; Hiroaki Mitsuya
Journal:  Angew Chem Int Ed Engl       Date:  2012-01-31       Impact factor: 15.336
  6 in total

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