Literature DB >> 30504991

Asymmetric Aldol Route to Hydroxyethylamine Isostere: Stereoselective Synthesis of the Core Unit of Saquinavir.

Arun K Ghosh1, Khaja Azhar Hussain1, Steve Fidanze1.   

Abstract

Entities:  

Year:  1997        PMID： 30504991      PMCID： PMC6261379          DOI： 10.1021/jo9706943

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


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  18 in total

1.  Total Synthesis of (+)-Sinefungin.

Authors:  Arun K. Ghosh; Wenming Liu
Journal:  J Org Chem       Date:  1996-09-06       Impact factor: 4.354

Review 2.  The retroviral enzymes.

Authors:  R A Katz; A M Skalka
Journal:  Annu Rev Biochem       Date:  1994       Impact factor: 23.643

3.  Highly Enantioselective Aldol Reaction: Development of a New Chiral Auxiliary from cis-1-Amino-2-hydroxyindan.

Authors:  Arun K Ghosh; Tien T Duong; Sean P McKee
Journal:  J Chem Soc Chem Commun       Date:  1992

4.  STEREOCONTROLLED SYNTHESIS OF HIV-l PROTEASE INHIBITORS WITH C2-AXIS OF SYMMETRY.

Authors:  Arun K Ghosh; Sean P McKee; Wayne J Thompson
Journal:  Tetrahedron Lett       Date:  2001-03-26       Impact factor: 2.415

5.  Diphenylphosphoryl azide. A new convenient reagent for a modified Curtus reaction and for the peptide synthesis.

Authors:  T Shioiri; K Ninomiya; S Yamada
Journal:  J Am Chem Soc       Date:  1972-08-23       Impact factor: 15.419

6.  Cyclic sulfolanes as novel and high affinity P2 ligands for HIV-1 protease inhibitors.

Authors:  A K Ghosh; W J Thompson; H Y Lee; S P McKee; P M Munson; T T Duong; P L Darke; J A Zugay; E A Emini; W A Schleif
Journal:  J Med Chem       Date:  1993-04-02       Impact factor: 7.446

7.  Inhibitors of HIV-1 protease containing the novel and potent (R)-(hydroxyethyl)sulfonamide isostere.

Authors:  M L Vazquez; M L Bryant; M Clare; G A DeCrescenzo; E M Doherty; J N Freskos; D P Getman; K A Houseman; J A Julien; G P Kocan
Journal:  J Med Chem       Date:  1995-02-17       Impact factor: 7.446

8.  Structure-based design of HIV-1 protease inhibitors: replacement of two amides and a 10 pi-aromatic system by a fused bis-tetrahydrofuran.

Authors:  A K Ghosh; W J Thompson; P M Fitzgerald; J C Culberson; M G Axel; S P McKee; J R Huff; P S Anderson
Journal:  J Med Chem       Date:  1994-08-05       Impact factor: 7.446

9.  Nonpeptidal P2 ligands for HIV protease inhibitors: structure-based design, synthesis, and biological evaluation.

Authors:  A K Ghosh; J F Kincaid; D E Walters; Y Chen; N C Chaudhuri; W J Thompson; C Culberson; P M Fitzgerald; H Y Lee; S P McKee; P M Munson; T T Duong; P L Darke; J A Zugay; W A Schleif; M G Axel; J Lin; J R Huff
Journal:  J Med Chem       Date:  1996-08-16       Impact factor: 7.446

10.  The development of cyclic sulfolanes as novel and high-affinity P2 ligands for HIV-1 protease inhibitors.

Authors:  A K Ghosh; H Y Lee; W J Thompson; C Culberson; M K Holloway; S P McKee; P M Munson; T T Duong; A M Smith; P L Darke
Journal:  J Med Chem       Date:  1994-04-15       Impact factor: 7.446
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  1 in total

Review 1.  The Curtius Rearrangement: Applications in Modern Drug Discovery and Medicinal Chemistry.

Authors:  Arun K Ghosh; Margherita Brindisi; Anindya Sarkar
Journal:  ChemMedChem       Date:  2018-10-11       Impact factor: 3.466
  1 in total

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