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Literature DB >> 7795534

Structural features of the uniporter/symporter/antiporter superfamily.

Abstract

The uniporter/symporter/antiporter superfamily is an evolutionarily related group of solute transporters. For the entire superfamily, we have used a new predictive program to identify the transmembrane domains. These transmembrane domains were then analyzed with regard to their overall hydrophobicity and amphipathicity. In addition, the lengths of the hydrophilic loops connecting the transmembrane domains were calculated. These data, together with structural information in the literature, were collectively used to produce a general model for the three-dimensional arrangement of the transmembrane domains.

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Year: 1995 PMID： 7795534 PMCID： PMC2143070 DOI： 10.1002/pro.5560040319

Source DB: PubMed Journal: Protein Sci ISSN： 0961-8368 Impact factor: 6.725

15 in total

Review 1. Membrane transport proteins: implications of sequence comparisons.

Authors: J K Griffith; M E Baker; D A Rouch; M G Page; R A Skurray; I T Paulsen; K F Chater; S A Baldwin; P J Henderson
Journal: Curr Opin Cell Biol Date: 1992-08 Impact factor: 8.382

2. A change of threonine 266 to isoleucine in the lac permease of Escherichia coli diminishes the transport of lactose and increases the transport of maltose.

Authors: M Markgraf; H Bocklage; B Müller-Hill
Journal: Mol Gen Genet Date: 1985

3. A model recognition approach to the prediction of all-helical membrane protein structure and topology.

Authors: D T Jones; W R Taylor; J M Thornton
Journal: Biochemistry Date: 1994-03-15 Impact factor: 3.162

4. A simple method for displaying the hydropathic character of a protein.

Authors: J Kyte; R F Doolittle
Journal: J Mol Biol Date: 1982-05-05 Impact factor: 5.469

5. Isolation and characterization of lactose permease mutants with an enhanced recognition of maltose and diminished recognition of cellobiose.

Authors: J C Collins; S F Permuth; R J Brooker
Journal: J Biol Chem Date: 1989-09-05 Impact factor: 5.157

6. Isolation and characterization of thiodigalactoside-resistant mutants of the lactose permease which possess an enhanced recognition for maltose.

Authors: P J Franco; J A Eelkema; R J Brooker
Journal: J Biol Chem Date: 1989-09-25 Impact factor: 5.157

Review 7. Proton-linked sugar transport systems in bacteria.

Authors: P J Henderson
Journal: J Bioenerg Biomembr Date: 1990-08 Impact factor: 2.945

8. The interaction between aspartic acid 237 and lysine 358 in the lactose carrier of Escherichia coli.

Authors: S C King; C L Hansen; T H Wilson
Journal: Biochim Biophys Acta Date: 1991-02-25

9. Mammalian and bacterial sugar transport proteins are homologous.

Authors: M C Maiden; E O Davis; S A Baldwin; D C Moore; P J Henderson
Journal: Nature Date: 1987 Feb 12-18 Impact factor: 49.962

Review 10. Nobel lecture. The photosynthetic reaction centre from the purple bacterium Rhodopseudomonas viridis.

Authors: J Deisenhofer; H Michel
Journal: EMBO J Date: 1989-08 Impact factor: 11.598

26 in total

Review 1. A functional-phylogenetic classification system for transmembrane solute transporters.

Authors: M H Saier
Journal: Microbiol Mol Biol Rev Date: 2000-06 Impact factor: 11.056

2. Second-site suppressor mutations of inactivating substitutions at gly247 of the tetracycline efflux protein, Tet(B).

Authors: C A Saraceni-Richards; S B Levy
Journal: J Bacteriol Date: 2000-11 Impact factor: 3.490

3. Structural model for 12-helix transporters belonging to the major facilitator superfamily.

Authors: Teruhisa Hirai; Jürgen A W Heymann; Peter C Maloney; Sriram Subramaniam
Journal: J Bacteriol Date: 2003-03 Impact factor: 3.490

4. Topology of OxlT, the oxalate transporter of Oxalobacter formigenes, determined by site-directed fluorescence labeling.

Authors: L Ye; Z Jia; T Jung; P C Maloney
Journal: J Bacteriol Date: 2001-04 Impact factor: 3.490

5. Control of H+/lactose coupling by ionic interactions in the lactose permease of Escherichia coli.

Authors: J L Johnson; R J Brooker
Journal: J Membr Biol Date: 2004-04-01 Impact factor: 1.843

6. Schizosaccharomyces pombe gene GHT1 is highly homologous to other prokaryotic, yeast and higher eukaryotic genes coding for monosaccharide transporters.

Authors: T Näschen; H C Lichtenberg-Fraté; S Ludwig; M Höfer
Journal: Folia Microbiol (Praha) Date: 1996 Impact factor: 2.099

7. Towards a new age of virtual ADME/TOX and multidimensional drug discovery.

Authors: Sean Ekins; Bruno Boulanger; Peter W Swaan; Maggie A Z Hupcey
Journal: J Comput Aided Mol Des Date: 2002 May-Jun Impact factor: 3.686

8. Suppressor scanning at positions 177 and 236 in the Escherichia coli lactose/H+ cotransporter and stereotypical effects of acidic substituents that suggest a favored orientation of transmembrane segments relative to the lipid bilayer.

Authors: S C King; S Li
Journal: J Bacteriol Date: 1998-05 Impact factor: 3.490

Review 9. Proton-dependent multidrug efflux systems.

Authors: I T Paulsen; M H Brown; R A Skurray
Journal: Microbiol Rev Date: 1996-12

10. Structural and functional importance of transmembrane domain 3 (TM3) in the aspartate:alanine antiporter AspT: topology and function of the residues of TM3 and oligomerization of AspT.

Authors: Kei Nanatani; Peter C Maloney; Keietsu Abe
Journal: J Bacteriol Date: 2009-01-30 Impact factor: 3.490