Literature DB >> 3892229

A change of threonine 266 to isoleucine in the lac permease of Escherichia coli diminishes the transport of lactose and increases the transport of maltose.

M Markgraf, H Bocklage, B Müller-Hill.   

Abstract

The DNA sequence of several functionally interesting lac permease mutants of Escherichia coli has been determined. The phenotypes of the mutant permeases were described by Mieschendahl et al. (1981). The following exchanges are noteworthy: tyr to asp in codon 26 in Y-K MUB 7; thr to ile in codon 266 in Y-K AJ 33; gly to asp in codon 262 in Y-D 3 and in Y-D 4.

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Year:  1985        PMID： 3892229     DOI： 10.1007/bf00332941

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN： 0026-8925


  15 in total

1.  Stoicheiometry of lactose-H+ symport across the plasma membrane of Escherichia coli.

Authors:  I C West; P Mitchell
Journal:  Biochem J       Date:  1973-03       Impact factor: 3.857

2.  Selective elimination of the exonuclease activity of the deoxyribonucleic acid polymerase from Escherichia coli B by limited proteolysis.

Authors:  H Klenow; I Henningsen
Journal:  Proc Natl Acad Sci U S A       Date:  1970-01       Impact factor: 11.205

3.  Supercoiled circular DNA-protein complex in Escherichia coli: purification and induced conversion to an opern circular DNA form.

Authors:  D B Clewell; D R Helinski
Journal:  Proc Natl Acad Sci U S A       Date:  1969-04       Impact factor: 11.205

4.  Functional molecular weight of the lac carrier protein from Escherichia coli as studied by radiation inactivation analysis.

Authors:  T Goldkorn; G Rimon; E S Kempner; H R Kaback
Journal:  Proc Natl Acad Sci U S A       Date:  1984-02       Impact factor: 11.205

5.  Mutations in the lacY gene of Escherichia coli define functional organization of lactose permease.

Authors:  M Mieschendahl; D Büchel; H Bocklage; B Müller-Hill
Journal:  Proc Natl Acad Sci U S A       Date:  1981-12       Impact factor: 11.205

Review 6.  The lac carrier protein in Escherichia coli.

Authors:  H R Kaback
Journal:  J Membr Biol       Date:  1983       Impact factor: 1.843

7.  Does the lactose carrier of Escherichia coli function as a monomer?

Authors:  J K Wright; U Weigel; A Lustig; H Bocklage; M Mieschendahl; B Müller-Hill; P Overath
Journal:  FEBS Lett       Date:  1983-10-03       Impact factor: 4.124

8.  pUR 250 allows rapid chemical sequencing of both DNA strands of its inserts.

Authors:  U Rüther
Journal:  Nucleic Acids Res       Date:  1982-10-11       Impact factor: 16.971

9.  Sequence of the lactose permease gene.

Authors:  D E Büchel; B Gronenborn; B Müller-Hill
Journal:  Nature       Date:  1980-02-07       Impact factor: 49.962

10.  Isolation of deoxyribonucleic acid methylase mutants of Escherichia coli K-12.

Authors:  M G Marinus; N R Morris
Journal:  J Bacteriol       Date:  1973-06       Impact factor: 3.490
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  13 in total

1.  Amino acid substitution in the lactose carrier protein with the use of amber suppressors.

Authors:  A M Huang; J I Lee; S C King; T H Wilson
Journal:  J Bacteriol       Date:  1992-08       Impact factor: 3.490

2.  Structural features of the uniporter/symporter/antiporter superfamily.

Authors:  V C Goswitz; R J Brooker
Journal:  Protein Sci       Date:  1995-03       Impact factor: 6.725

3.  Molecular cloning of the phosphate (inorganic) transport (pit) gene of Escherichia coli K12. Identification of the pit+ gene product and physical mapping of the pit-gor region of the chromosome.

Authors:  C M Elvin; N E Dixon; H Rosenberg
Journal:  Mol Gen Genet       Date:  1986-09

4.  Evidence for the transport of maltose by the sucrose permease, CscB, of Escherichia coli.

Authors:  Yang Peng; Sanath Kumar; Ricardo L Hernandez; Suzanna E Jones; Kathleen M Cadle; Kenneth P Smith; Manuel F Varela
Journal:  J Membr Biol       Date:  2009-03-18       Impact factor: 1.843

5.  Proline transport in Salmonella typhimurium: putP permease mutants with altered substrate specificity.

Authors:  D K Dila; S R Maloy
Journal:  J Bacteriol       Date:  1986-11       Impact factor: 3.490

6.  Lactose permease mutants which transport (malto)-oligosaccharides.

Authors:  S G Olsen; K M Greene; R J Brooker
Journal:  J Bacteriol       Date:  1993-10       Impact factor: 3.490

7.  Lactose permease of Escherichia coli: properties of mutants defective in substrate translocation.

Authors:  P Overath; U Weigel; J M Neuhaus; J Soppa; R Seckler; I Riede; H Bocklage; B Müller-Hill; G Aichele; J K Wright
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

8.  Amino acids that confer transport of raffinose and maltose sugars in the raffinose permease (RafB) of Escherichia coli as implicated by spontaneous mutations at Val-35, Ser-138, Ser-139, Gly-389 and Ile-391.

Authors:  Bonnie M Van Camp; Robert R Crow; Yang Peng; Manuel F Varela
Journal:  J Membr Biol       Date:  2007-11-17       Impact factor: 1.843

9.  Potato sucrose transporter expression in minor veins indicates a role in phloem loading.

Authors:  J W Riesmeier; B Hirner; W B Frommer
Journal:  Plant Cell       Date:  1993-11       Impact factor: 11.277

10.  Truncated forms of Escherichia coli lactose permease: models for study of biosynthesis and membrane insertion.

Authors:  U Stochaj; H J Fritz; C Heibach; M Markgraf; A von Schaewen; U Sonnewald; R Ehring
Journal:  J Bacteriol       Date:  1988-06       Impact factor: 3.490
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