Literature DB >> 773728

High concentration of somatostatin immunoreactivity in chicken pancreas.

G C Weir, P C Goltsos, E P Steinberg, Y C Patel.   

Abstract

Extracts of discrete lobes of chicken pancreas were assayed for somatostatin (SRIF), insulin and glucagon immunoreactivity. The distribution of hormone concentration was correlated appropriately with the known distribution of A, B, and D-cells. Concentrations of all three hormones were highest in the splenic lobe. The glucagon content of the ventral and dorsal lobes was low. Evidence is presented that the SRIF-like material in the pancreatic extracts is very similar to synthetic cyclic SRIF; parallel immunoassay displacement curves and similar chromatographic elution profiles were obtained. The SRIF concentration in chicken pancreas is 21 times higher than that found in the rat. Chicken pancreas may provide a useful model for studies of somatostatin physiology.

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Year:  1976        PMID： 773728     DOI： 10.1007/bf00428977

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


  20 in total

1.  Immunoreactive somatostatin is present in discrete cells of the endocrine pancreas.

Authors:  M P Dubois
Journal:  Proc Natl Acad Sci U S A       Date:  1975-04       Impact factor: 11.205

2.  Inhibition by somatostatin of ACTH secretion in Nelson's syndrome.

Authors:  J B Tyrrell; M Lorenzi; J E Gerich; P H Forsham
Journal:  J Clin Endocrinol Metab       Date:  1975-06       Impact factor: 5.958

3.  Somatostatin: hypothalamic inhibitor of the endocrine pancreas.

Authors:  D J Koerker; W Ruch; E Chideckel; J Palmer; C J Goodner; J Ensinck; C C Gale
Journal:  Science       Date:  1974-04-26       Impact factor: 47.728

4.  Inhibition of gastrin and gastric-acid secretion by growth-hormone release-inhibiting hormone.

Authors:  S R Bloom; C H Mortimer; M O Thorner; G M Besser; R Hall; A Gomez-Pan; V M Roy; R C Russell; D H Coy; A J Kastin; A V Schally
Journal:  Lancet       Date:  1974-11-09       Impact factor: 79.321

5.  Studies of the distribution of a new avian pancreatic polypeptide and insulin among birds, reptiles, amphibians and mammals.

Authors:  D R Langslow; J R Kimmel; H G Pollock
Journal:  Endocrinology       Date:  1973-09       Impact factor: 4.736

Review 6.  D cell, the third endocrine element of the pancreatic islet.

Authors:  T Fujita
Journal:  Arch Histol Jpn       Date:  1968-02

7.  Growth-hormone release-inhibiting hormone in gastrointestinal and pancreatic D cells.

Authors:  J M Polak; A G Pearse; L Grimelius; S R Bloom
Journal:  Lancet       Date:  1975-05-31       Impact factor: 79.321

8.  [Effect of somatostatin on betazole-stimulated gastric secretion and carbachol-stimulated pancreatic secretion and gall bladder contraction in man(author's transl)].

Authors:  P G Lankisch; R Arnold; W Creuzfeldt
Journal:  Dtsch Med Wochenschr       Date:  1975-09-05       Impact factor: 0.628

9.  Insulin and glucose as modulators of the amino acid-induced glucagon release in the isolated pancreas of alloxan and streptozotocin diabetic rats.

Authors:  A S Pagliara; S N Stillings; M W Haymond; B A Hover; F M Matschinsky
Journal:  J Clin Invest       Date:  1975-02       Impact factor: 14.808

10.  [Inhibition by somatostatin of pancreatic juice and enzyme secretion and gallbladder contraction in man induced by secretin and cholecystokinin-pancreozymin administration (author's transl)].

Authors:  W Creutzfeldt; P G Lankisch; U R Fölsch
Journal:  Dtsch Med Wochenschr       Date:  1975-05-16       Impact factor: 0.628
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  11 in total

1.  Peptidergic hormones and neuropeptides, and aminergic neurotransmitters of the pancreatic islets of the Houbara bustard (Chlamydotis undulata).

Authors:  E P Mensah-Brown; T A Bailey; D J Pallot; A Garner
Journal:  J Anat       Date:  2000-02       Impact factor: 2.610

2.  Distribution, ontogeny and ultrastructure of somatostatin immunoreactive cells in the pancreas and gut.

Authors:  J Alumets; F Sundler; R Håkanson
Journal:  Cell Tissue Res       Date:  1977-12-28       Impact factor: 5.249

Review 3.  Modeling chick to assess diabetes pathogenesis and treatment.

Authors:  Savita P Datar; Ramesh R Bhonde
Journal:  Rev Diabet Stud       Date:  2011-08-10

4.  Adrenergic modulation of pancreatic A, B, and D cells alpha-Adrenergic suppression and beta-adrenergic stimulation of somatostatin secretion, alpha-adrenergic stimulation of glucagon secretion in the perfused dog pancreas.

Authors:  E Samols; G C Weir
Journal:  J Clin Invest       Date:  1979-02       Impact factor: 14.808

5.  A transplantable insulinoma in the rat.

Authors:  W L Chick; S Warren; R N Chute; A A Like; V Lauris; K C Kitchen
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

6.  Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release.

Authors:  S Bonner-Weir; D F Trent; G C Weir
Journal:  J Clin Invest       Date:  1983-06       Impact factor: 14.808

7.  Gastrointestinal somatostatin: extraction and radioimmunoassay in different species.

Authors:  C McIntosh; R Arnold; E Bothe; H Becker; J Köbberling; W Creutzfeldt
Journal:  Gut       Date:  1978-07       Impact factor: 23.059

8.  Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor.

Authors:  A F Gazdar; W L Chick; H K Oie; H L Sims; D L King; G C Weir; V Lauris
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

9.  Somatostatin stimulates glucagon secretion in ducks.

Authors:  M T Strosser; L Cohen; S Harvey; P Mialhe
Journal:  Diabetologia       Date:  1980-04       Impact factor: 10.122

10.  Isolation and characterization of immunoreactive somatostatin from fish pancreatic islets.

Authors:  H Oyama; H J Hirsch; K H Gabbay; A Permutt
Journal:  J Clin Invest       Date:  1980-05       Impact factor: 14.808
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