| Literature DB >> 4594711 |
D J Koerker, W Ruch, E Chideckel, J Palmer, C J Goodner, J Ensinck, C C Gale.
Abstract
Somatostatin, a hypothalamic peptide that inhibits the secretion of pituitary growth hormone, inhibits basal insulin secretion in fasted cats and rats. In fasted baboons both basal and arginine-stimulated secretion of insulin and glucagon are inhibited. Somatostatin appears to act directly on the endocrine pancreas. The action is dose-related, rapid in onset, and readily reversed.Entities:
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Year: 1974 PMID： 4594711 DOI： 10.1126/science.184.4135.482
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728