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Literature DB >> 1126301

[Inhibition by somatostatin of pancreatic juice and enzyme secretion and gallbladder contraction in man induced by secretin and cholecystokinin-pancreozymin administration (author's transl)].

W Creutzfeldt, P G Lankisch, U R Fölsch.

Abstract

Somatostatin (200 mug/h) was administered to five healthy volunteers after submaximal stimulation of exocrine pancreatic secretion with 0.33 KU secretin or cholecystokinin-pancreozymin, given intravenously. In all instances there was a significant reduction in duodenal secretory volume after secretin, without any change in HCO3- concentration. Stimulation of enzyme secretion by cholecystokinin-pancreozymin was significantly inhibited and gallbladder contraction abolished.

Entities: Chemical Disease Gene Species

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Year: 1975 PMID： 1126301

Source DB: PubMed Journal: Dtsch Med Wochenschr ISSN： 0012-0472 Impact factor: 0.628

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Cited

21 in total

1. Immuno-fluorescent reactivity to anti-somatostatin in the gastro-intestinal mucosa of the dog.

Authors: C Rufener; M P Dubois; F Malaisse Lagae; L Oric
Journal: Diabetologia Date: 1975-08 Impact factor: 10.122

2. The effect of somatostatin on the response of GLI to the intraduodenal administration of glucose, protein, and fat.

Authors: H Sakurai; R E Dobbs; R H Unger
Journal: Diabetologia Date: 1975-10 Impact factor: 10.122

3. The effects of gastrin, gastric inhibitory polypeptide, secretin, and the octapeptide of cholecystokinin upon immunoreactive somatostatin release by the perfused canine pancreas.

Authors: E Ipp; R E Dobbs; V Harris; A Arimura; W Vale; R H Unger
Journal: J Clin Invest Date: 1977-11 Impact factor: 14.808

4. Leukocyte response to somatostatin in normals and patients with bacterial leukocytosis.

Authors: E Zierden; K Hengst; H Wagner
Journal: Klin Wochenschr Date: 1977-05-15

5. Cholescintigraphic study of effect of somatostatin analog, octreotide, on bile secretion and gallbladder emptying in normal subjects.

Authors: C Grimaldi; J Darcourt; A G Harris; E Lebot; F Lapalus; J Delmont
Journal: Dig Dis Sci Date: 1993-09 Impact factor: 3.199

[Inhibition by somatostatin of pancreatic juice and enzyme secretion and gallbladder contraction in man induced by secretin and cholecystokinin-pancreozymin administration (author's transl)].

1. Immuno-fluorescent reactivity to anti-somatostatin in the gastro-intestinal mucosa of the dog.

2. The effect of somatostatin on the response of GLI to the intraduodenal administration of glucose, protein, and fat.

3. The effects of gastrin, gastric inhibitory polypeptide, secretin, and the octapeptide of cholecystokinin upon immunoreactive somatostatin release by the perfused canine pancreas.

4. Leukocyte response to somatostatin in normals and patients with bacterial leukocytosis.

5. Cholescintigraphic study of effect of somatostatin analog, octreotide, on bile secretion and gallbladder emptying in normal subjects.

Review 6. Gall-bladder water and electrolyte transport and its regulation.

Review 7. The milieu interieur and the islets of Langerhans.

8. Somatostatin and the intestinal transport of glucose and other nutrients in the anaesthetised rat.

9. Coagulation studies and platelet function after somatostatin infusion.

10. Effect of somatostatin 14 on pure human pancreatic secretion.