Literature DB >> 1093177

Immunoreactive somatostatin is present in discrete cells of the endocrine pancreas.

M P Dubois.   

Abstract

A discrete population of cells of the endocrine pancreas contains immunoreactive somatostatin as shown by immunofluorescence. These cells are different from those containing glucagon or insulin. This unexpected observation may be of physiopathological significance in the regulatory mechanisms involved in the secretion of glucagon and insulin.

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Year:  1975        PMID: 1093177      PMCID: PMC432529          DOI: 10.1073/pnas.72.4.1340

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  8 in total

1.  Electron microscopic description of a third cell type in the islets of the rat pancreas.

Authors:  F CARAMIA
Journal:  Am J Anat       Date:  1963-01

2.  Electron microscopic immunohistochemical localization of growth hormone-release inhibiting hormone (somatostatin) in the rat median eminence.

Authors:  G Pelletier; F Labrie; A Arimura; A V Schally
Journal:  Am J Anat       Date:  1974-07

3.  Immunohistochemical localization of somatostatin (growth hormone release-inhibiting factor) in the guinea pig brain.

Authors:  T Hökfelt; S Efendic; O Johansson; R Luft; A Arimura
Journal:  Brain Res       Date:  1974-11-08       Impact factor: 3.252

4.  Somatostatin. Total solid phase synthesis.

Authors:  J E Rivier
Journal:  J Am Chem Soc       Date:  1974-05-01       Impact factor: 15.419

5.  [Preliminary observations on the mechanism of action of somatostatin, a hypothalamic factor inhibiting the secretion of growth hormone].

Authors:  W Vale; P Brazeau; G Grant; A Nussey; R Burgus; J Rivier; N Ling; R Guillemin
Journal:  C R Acad Hebd Seances Acad Sci D       Date:  1972-12-18

Review 6.  The neural ectodermal origin of the peptide-secreting endocrine glands. A unifying concept for the etiology of multiple endocrine adenomatosis and the inappropriate secretion of peptide hormones by nonendocrine tumors.

Authors:  R F Weichert
Journal:  Am J Med       Date:  1970-08       Impact factor: 4.965

7.  Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone.

Authors:  P Brazeau; W Vale; R Burgus; N Ling; M Butcher; J Rivier; R Guillemin
Journal:  Science       Date:  1973-01-05       Impact factor: 47.728

8.  Primary structure of somatostatin, a hypothalamic peptide that inhibits the secretion of pituitary growth hormone.

Authors:  R Burgus; N Ling; M Butcher; R Guillemin
Journal:  Proc Natl Acad Sci U S A       Date:  1973-03       Impact factor: 11.205

  8 in total
  72 in total

1.  Immuno-fluorescent reactivity to anti-somatostatin in the gastro-intestinal mucosa of the dog.

Authors:  C Rufener; M P Dubois; F Malaisse Lagae; L Oric
Journal:  Diabetologia       Date:  1975-08       Impact factor: 10.122

2.  Topographical relationships between catecholamine- and neuropeptide-containing fibers in the median eminence of the newt, Triturus alpestris. An ultrastructural immunocytochemical study.

Authors:  M Corio; J Thibault; J Peute
Journal:  Cell Tissue Res       Date:  1990-03       Impact factor: 5.249

3.  Immunocytochemical study of the endocrine pancreas in the grey kangaroo (Macropus fuliginosus).

Authors:  N Edwin; C M Leigh
Journal:  Cell Tissue Res       Date:  1990-01       Impact factor: 5.249

4.  Release of somatostatin-like immunoreactivity from incubated rat hypothalamus and cerebral cortex. Effects of glucose and glucoregulatory hormones.

Authors:  M Berelowitz; D Dudlak; L A Frohman
Journal:  J Clin Invest       Date:  1982-06       Impact factor: 14.808

5.  Vasoactive intestinal peptide (VIP) cells in the pancrease and gastro-intestinal mucosa. An immunohistochemical and ultrastructural study.

Authors:  R Buffa; C Capella; E Solcia; B Frigerio; S I Said
Journal:  Histochemistry       Date:  1977-01-24

6.  Pancreatic immunoreactive somatostatin release.

Authors:  G S Patton; E Ipp; R E Dobbs; L Orci; W Vale; R H Unger
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205

7.  Previous exposure to glucose enhances somatostatin secretion from the isolated perfused rat pancreas.

Authors:  V Grill; M Rundfeldt; S Efendić
Journal:  Diabetologia       Date:  1981-04       Impact factor: 10.122

8.  [Ultrastructural identification and immunocytochemical study of somatostatin cells in antral mucosa of the rabbit and the mouse (author's transl)].

Authors:  A L'Hermite; G Lefrane; G Pradal; M J Andreé; M P Dubois
Journal:  Histochemistry       Date:  1976-04-21

9.  Properties of endogenous somatostatin-like immunoreactivity and synthetic somatostatin in dog plasma.

Authors:  J M Conlon; C B Srikant; E Ipp; V Schusdziarra; W Vale; R H Unger
Journal:  J Clin Invest       Date:  1978-12       Impact factor: 14.808

10.  An immunocytochemical study of the distribution of pancreatic endocrine cells in chicks, with special reference to the relationship between pancreatic polypeptide and somatostatin-immunoreactive cells.

Authors:  B B Rawdon; A Andrew
Journal:  Histochemistry       Date:  1979-01-22
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