Literature DB >> 7726535

DNA gyrase mutations in quinolone-resistant clinical isolates of Neisseria gonorrhoeae.

T Deguchi1, M Yasuda, M Asano, K Tada, H Iwata, H Komeda, T Ezaki, I Saito, Y Kawada.   

Abstract

Eight quinolone-resistant clinical isolates of Neisseria gonorrhoeae were shown to carry mutations in their GyrA proteins. Six isolates had a single amino acid change of serine to phenylalanine at the position corresponding to Ser-83 in Escherichia coli. In addition to the change of serine to phenylalanine, two isolates had another change of aspartic acid to asparagine at the position corresponding to Asp-87 in E. coli.

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Year:  1995        PMID： 7726535      PMCID： PMC162582          DOI： 10.1128/AAC.39.2.561

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  20 in total

1.  Ciprofloxacin resistance in gonococci.

Authors:  A E Jephcott; A Turner
Journal:  Lancet       Date:  1990-01-20       Impact factor: 79.321

2.  Decreased susceptibility of Neisseria gonorrhoeae to ciprofloxacin.

Authors:  W R Gransden; C A Warren; I Phillips; M Hodges; D Barlow
Journal:  Lancet       Date:  1990-01-06       Impact factor: 79.321

3.  Mapping the active site tyrosine of Escherichia coli DNA gyrase.

Authors:  D S Horowitz; J C Wang
Journal:  J Biol Chem       Date:  1987-04-15       Impact factor: 5.157

4.  Cloning and sequencing of the Escherichia coli gyrA gene coding for the A subunit of DNA gyrase.

Authors:  S L Swanberg; J C Wang
Journal:  J Mol Biol       Date:  1987-10-20       Impact factor: 5.469

5.  Oral ciprofloxacin versus ceftriaxone for the treatment of urethritis from resistant Neisseria gonorrhoeae in Zambia.

Authors:  J P Bryan; S K Hira; W Brady; N Luo; C Mwale; G Mpoko; R Krieg; E Siwiwaliondo; C Reichart; C Waters
Journal:  Antimicrob Agents Chemother       Date:  1990-05       Impact factor: 5.191

6.  A single point mutation in the DNA gyrase A protein greatly reduces binding of fluoroquinolones to the gyrase-DNA complex.

Authors:  C J Willmott; A Maxwell
Journal:  Antimicrob Agents Chemother       Date:  1993-01       Impact factor: 5.191

7.  Structure and function of the region of the replication origin of the Bacillus subtilis chromosome. III. Nucleotide sequence of some 10,000 base pairs in the origin region.

Authors:  S Moriya; N Ogasawara; H Yoshikawa
Journal:  Nucleic Acids Res       Date:  1985-04-11       Impact factor: 16.971

8.  Cloning and characterization of a DNA gyrase A gene from Escherichia coli that confers clinical resistance to 4-quinolones.

Authors:  M E Cullen; A W Wyke; R Kuroda; L M Fisher
Journal:  Antimicrob Agents Chemother       Date:  1989-06       Impact factor: 5.191

9.  Cloning and nucleotide sequence of Mycobacterium tuberculosis gyrA and gyrB genes and detection of quinolone resistance mutations.

Authors:  H E Takiff; L Salazar; C Guerrero; W Philipp; W M Huang; B Kreiswirth; S T Cole; W R Jacobs; A Telenti
Journal:  Antimicrob Agents Chemother       Date:  1994-04       Impact factor: 5.191

10.  Cloning and nucleotide sequence of the Campylobacter jejuni gyrA gene and characterization of quinolone resistance mutations.

Authors:  Y Wang; W M Huang; D E Taylor
Journal:  Antimicrob Agents Chemother       Date:  1993-03       Impact factor: 5.191
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  33 in total

1.  An invasive isolate of Neisseria meningitidis showing decreased susceptibility to quinolones.

Authors:  T R Shultz; J W Tapsall; P A White; P J Newton
Journal:  Antimicrob Agents Chemother       Date:  2000-04       Impact factor: 5.191

2.  [Neisseria gonorrhoeae infection in an area of Madrid: 1997-1999].

Authors:  M Alonso-Sanz; M Abad
Journal:  Aten Primaria       Date:  2001-03-31       Impact factor: 1.137

3.  Mutation patterns in gyrA and parC genes of ciprofloxacin resistant isolates of Neisseria gonorrhoeae from India.

Authors:  U Chaudhry; K Ray; M Bala; D Saluja
Journal:  Sex Transm Infect       Date:  2002-12       Impact factor: 3.519

4.  Emergence and spread of Neisseria gonorrhoeae clinical isolates harboring mosaic-like structure of penicillin-binding protein 2 in Central Japan.

Authors:  Masayasu Ito; Takashi Deguchi; Koh-Suke Mizutani; Mitsuru Yasuda; Shigeaki Yokoi; Shin-Ichi Ito; Yoshito Takahashi; Satoshi Ishihara; Yoshiaki Kawamura; Takayuki Ezaki
Journal:  Antimicrob Agents Chemother       Date:  2005-01       Impact factor: 5.191

5.  Identification of novel mutation patterns in the parC gene of ciprofloxacin-resistant isolates of Neisseria gonorrhoeae.

Authors:  D L Trees; A L Sandul; W L Whittington; J S Knapp
Journal:  Antimicrob Agents Chemother       Date:  1998-08       Impact factor: 5.191

Review 6.  Antimicrobial agents and gonorrhoea: therapeutic choice, resistance and susceptibility testing.

Authors:  C A Ison
Journal:  Genitourin Med       Date:  1996-08

7.  Cloning and nucleotide sequence of the DNA gyrase gyrA gene from the fish pathogen Aeromonas salmonicida.

Authors:  H Oppegaard; H Sørum
Journal:  Antimicrob Agents Chemother       Date:  1996-05       Impact factor: 5.191

8.  Drift in susceptibility of Neisseria gonorrhoeae to ciprofloxacin and emergence of therapeutic failure.

Authors:  C A Ison; P J Woodford; H Madders; E Claydon
Journal:  Antimicrob Agents Chemother       Date:  1998-11       Impact factor: 5.191

9.  Quinolone-resistant Neisseria gonorrhoeae: correlation of alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV with antimicrobial susceptibility profiles.

Authors:  T Deguchi; M Yasuda; M Nakano; S Ozeki; T Ezaki; I Saito; Y Kawada
Journal:  Antimicrob Agents Chemother       Date:  1996-04       Impact factor: 5.191

10.  Sequence of quinolone resistance-determining region of gyrA gene for clinical isolates and for an in vitro-selected quinolone-resistant strain of Coxiella burnetii.

Authors:  D Musso; M Drancourt; S Osscini; D Raoult
Journal:  Antimicrob Agents Chemother       Date:  1996-04       Impact factor: 5.191
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