K K Watanabe1, H K Kang, N A Dalager. 1. Environmental Epidemiology Service, Department of Veterans Affairs, Washington, DC 20036-3406, USA.
Abstract
OBJECTIVES: This study was undertaken to determine if Navy veterans who participated in an atmospheric nuclear test in 1958 were at increased risk of death from certain cancers. METHODS: Cancer mortality risk of 8554 Navy veterans who participated in an atmospheric nuclear test in the Pacific was compared with that of 14,625 Navy veterans who did not participate in any test. Radiation dosage information was obtained from film badges for 88% of the test participants. RESULTS: The median radiation dose for the test participants was 388 mrem (3.88 millisieverts [mSv]). Among participants who received the highest radiation dose (> 1000 mrem, or 10 mSv), an increased mortality risk for all causes (relative risk [RR] = 1.23; 95% confidence interval [CI] = 1.04, 1.45), all cancers (RR = 1.42; 95% CI = 1.03, 1.96), and liver cancer (RR = 6.42; 95% CI = 1.17, 35.3) was observed. The risk for cancer of the digestive organs was elevated among test participants (rate ratio = 1.47; 95% CI = 1.06, 2.04) but with no significant dose-response trend. Many of the cancers of a priori interest were not significantly elevated in the overall test participant group or in the group that received the highest radiation dose. CONCLUSIONS: Most of the cancers suspected of being radiogenic were not significantly elevated among the test participants. Nevertheless, increased risks for certain cancers cannot be ruled out at this time. Veterans who participated in the nuclear weapons tests should continue to be monitored.
OBJECTIVES: This study was undertaken to determine if Navy veterans who participated in an atmospheric nuclear test in 1958 were at increased risk of death from certain cancers. METHODS:Cancer mortality risk of 8554 Navy veterans who participated in an atmospheric nuclear test in the Pacific was compared with that of 14,625 Navy veterans who did not participate in any test. Radiation dosage information was obtained from film badges for 88% of the test participants. RESULTS: The median radiation dose for the test participants was 388 mrem (3.88 millisieverts [mSv]). Among participants who received the highest radiation dose (> 1000 mrem, or 10 mSv), an increased mortality risk for all causes (relative risk [RR] = 1.23; 95% confidence interval [CI] = 1.04, 1.45), all cancers (RR = 1.42; 95% CI = 1.03, 1.96), and liver cancer (RR = 6.42; 95% CI = 1.17, 35.3) was observed. The risk for cancer of the digestive organs was elevated among test participants (rate ratio = 1.47; 95% CI = 1.06, 2.04) but with no significant dose-response trend. Many of the cancers of a priori interest were not significantly elevated in the overall test participant group or in the group that received the highest radiation dose. CONCLUSIONS: Most of the cancers suspected of being radiogenic were not significantly elevated among the test participants. Nevertheless, increased risks for certain cancers cannot be ruled out at this time. Veterans who participated in the nuclear weapons tests should continue to be monitored.
Authors: Glyn G Caldwell; Matthew M Zack; Michael T Mumma; Henry Falk; Clark W Heath; John E Till; Heidi Chen; John D Boice Journal: J Radiol Prot Date: 2016-06-29 Impact factor: 1.394
Authors: John E Till; Harold L Beck; Jill W Aanenson; Helen A Grogan; H Justin Mohler; S Shawn Mohler; Paul G Voillequé Journal: Radiat Res Date: 2014-04-23 Impact factor: 2.841
Authors: André Bouville; Richard E Toohey; John D Boice; Harold L Beck; Larry T Dauer; Keith F Eckerman; Derek Hagemeyer; Richard W Leggett; Michael T Mumma; Bruce Napier; Kathy H Pryor; Marvin Rosenstein; David A Schauer; Sami Sherbini; Daniel O Stram; James L Thompson; John E Till; Craig Yoder; Cary Zeitlin Journal: Health Phys Date: 2015-02 Impact factor: 1.316