| Literature DB >> 7684473 |
G Borisova1, B Arya, A Dislers, O Borschukova, V Tsibinogin, D Skrastina, M A Eldarov, P Pumpens, K G Skryabin, E Grens.
Abstract
A hepatitis B core antigen (HBcAg) gene bearing the 39-amino-acid-long domain A of hepatitis B surface antigen (HBsAg) within the HBcAg immunodominant loop has been constructed and expressed in Escherichia coli. Chimeric capsids demonstrated HBs but not HBc antigenicity and elicited in mice B-cell and T-cell responses against native HBcAg and HBsAg.Entities:
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Year: 1993 PMID: 7684473 PMCID: PMC237728
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103