Literature DB >> 7666986

The enzymatic cleavage of beta-carotene: still controversial.

G Wolf1.   

Abstract

The enzyme beta-carotene-15,15'-dioxygenase from guinea pig intestinal mucosa was found to cleave beta-carotene and produce 2 mol of retinal for 1 mol of beta-carotene. However, extensive evidence exists also for random (excentric) cleavage, resulting in retinoic acid and retinal, with a preponderance of apocarotenals formed as intermediates.

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Year:  1995        PMID： 7666986     DOI： 10.1111/j.1753-4887.1995.tb01537.x

Source DB:  PubMed          Journal:  Nutr Rev        ISSN： 0029-6643            Impact factor:   7.110


  8 in total

1.  In vitro characterization of a recombinant Blh protein from an uncultured marine bacterium as a beta-carotene 15,15'-dioxygenase.

Authors:  Yeong-Su Kim; Nam-Hee Kim; Soo-Jin Yeom; Seon-Won Kim; Deok-Kun Oh
Journal:  J Biol Chem       Date:  2009-04-14       Impact factor: 5.157

Review 2.  Structural and mechanistic aspects of carotenoid cleavage dioxygenases (CCDs).

Authors:  Anahita Daruwalla; Philip D Kiser
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2019-12-23       Impact factor: 4.698

3.  Expression pattern and localization of beta,beta-carotene 15,15'-dioxygenase in different tissues.

Authors:  A Wyss; G M Wirtz; W D Woggon; R Brugger; M Wyss; A Friedlein; G Riss; H Bachmann; W Hunziker
Journal:  Biochem J       Date:  2001-03-15       Impact factor: 3.857

Review 4.  The molecular aspects of absorption and metabolism of carotenoids and retinoids in vertebrates.

Authors:  Made Airanthi K Widjaja-Adhi; Marcin Golczak
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2019-11-23       Impact factor: 4.698

5.  Nutrient plasma levels achieved during treatment that reduces noise-induced hearing loss.

Authors:  Colleen G Le Prell; David F Dolan; David C Bennett; Peter A Boxer
Journal:  Transl Res       Date:  2011-03-09       Impact factor: 7.012

6.  Mutation in bovine beta-carotene oxygenase 2 affects milk color.

Authors:  S D Berry; S R Davis; E M Beattie; N L Thomas; A K Burrett; H E Ward; A M Stanfield; M Biswas; A E Ankersmit-Udy; P E Oxley; J L Barnett; J F Pearson; Y van der Does; A H K Macgibbon; R J Spelman; K Lehnert; R G Snell
Journal:  Genetics       Date:  2009-04-27       Impact factor: 4.562

7.  Two carotenoid oxygenases contribute to mammalian provitamin A metabolism.

Authors:  Jaume Amengual; M Airanthi K Widjaja-Adhi; Susana Rodriguez-Santiago; Susanne Hessel; Marcin Golczak; Krzysztof Palczewski; Johannes von Lintig
Journal:  J Biol Chem       Date:  2013-10-08       Impact factor: 5.157

Review 8.  Roles of Vitamin A Metabolism in the Development of Hepatic Insulin Resistance.

Authors:  Guoxun Chen
Journal:  ISRN Hepatol       Date:  2013-09-30
  8 in total

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