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Literature DB >> 7559980

Tear fluid of hepatitis C virus carriers could be infectious.

H H Feucht¹, B Zöllner, M Schröter, H Altrogge, R Laufs.

Abstract

For up to 20 to 40% of patients chronically infected with hepatitis C virus (HCV), the mode of transmission is still unknown. We demonstrate that tear fluid contains HCV RNA-carrying material with the properties of infectious virus and conclude that smear infection with tear fluid may play a role in HCV transmission.

Entities: Disease Species

Mesh：

Substances：
RNA, Viral

Year: 1995 PMID： 7559980 PMCID： PMC228367 DOI： 10.1128/jcm.33.8.2202-2203.1995

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

8 in total

1. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

Authors: P Chomczynski; N Sacchi
Journal: Anal Biochem Date: 1987-04 Impact factor: 3.365

2. Density heterogeneities of hepatitis C virus in human sera due to the binding of beta-lipoproteins and immunoglobulins.

Authors: R Thomssen; S Bonk; A Thiele
Journal: Med Microbiol Immunol Date: 1993-12 Impact factor: 3.402

3. Detection of hepatitis C virus RNA in tears and aqueous humor.

Authors: J Shimazaki; K Tsubota; Y Fukushima; M Honda
Journal: Am J Ophthalmol Date: 1994-10-15 Impact factor: 5.258

4. Study on reliability of commercially available hepatitis C virus antibody tests.

Authors: H H Feucht; B Zöllner; S Polywka; R Laufs
Journal: J Clin Microbiol Date: 1995-03 Impact factor: 5.948

5. The natural history of community-acquired hepatitis C in the United States. The Sentinel Counties Chronic non-A, non-B Hepatitis Study Team.

Authors: M J Alter; H S Margolis; K Krawczynski; F N Judson; A Mares; W J Alexander; P Y Hu; J K Miller; M A Gerber; R E Sampliner
Journal: N Engl J Med Date: 1992-12-31 Impact factor: 91.245

6. Greater amount of HCV-RNA in tears compared to blood.

Authors: H H Feucht; S Polywka; B Zöllner; R Laufs
Journal: Microbiol Immunol Date: 1994 Impact factor: 1.955

7. Equilibrium centrifugation studies of hepatitis C virus: evidence for circulating immune complexes.

Authors: M Hijikata; Y K Shimizu; H Kato; A Iwamoto; J W Shih; H J Alter; R H Purcell; H Yoshikura
Journal: J Virol Date: 1993-04 Impact factor: 5.103

8. Classification of hepatitis C virus into six major genotypes and a series of subtypes by phylogenetic analysis of the NS-5 region.

Authors: P Simmonds; E C Holmes; T A Cha; S W Chan; F McOmish; B Irvine; E Beall; P L Yap; J Kolberg; M S Urdea
Journal: J Gen Virol Date: 1993-11 Impact factor: 3.891

8 in total

7 in total

Tear fluid of hepatitis C virus carriers could be infectious.

1. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

2. Density heterogeneities of hepatitis C virus in human sera due to the binding of beta-lipoproteins and immunoglobulins.

3. Detection of hepatitis C virus RNA in tears and aqueous humor.

4. Study on reliability of commercially available hepatitis C virus antibody tests.

5. The natural history of community-acquired hepatitis C in the United States. The Sentinel Counties Chronic non-A, non-B Hepatitis Study Team.

6. Greater amount of HCV-RNA in tears compared to blood.

7. Equilibrium centrifugation studies of hepatitis C virus: evidence for circulating immune complexes.

8. Classification of hepatitis C virus into six major genotypes and a series of subtypes by phylogenetic analysis of the NS-5 region.

1. Definition of false-positive reactions in screening for hepatitis C virus antibodies.

2. Hepatitis C: increasing knowledge and unresolved questions.

3. Quantitative detection of hepatitis C virus RNA by light cycler PCR and comparison with two different PCR assays.

4. Distribution of genotypes and response to alpha-interferon in patients with hepatitis C virus infection in Germany.

Review 5. Ocular tropism of respiratory viruses.

6. The severe acute respiratory syndrome coronavirus in tears.

Review 7. A Systematic Review Regarding Tonometry and the Transmission of Infectious Diseases.