Literature DB >> 7319904

Virantmycin, a new antiviral antibiotic produced by a strain of Streptomyces.

A Nakagawa, Y Iwai, H Hashimoto, N Miyazaki, R Oiwa, Y Takahashi, A Hirano, N Shibukawa, Y Kojima, S Omura.   

Abstract

Virantmycin, a novel chlorine-containing antiviral antibiotic, has been isolated from Streptomyces nitrosporeus No. AM-2722. The active substance in culture broth is isolated as colorless needles by solvent extraction followed by high performance liquid chromatography on silicic acid. The molecular formula is C19H26NO3Cl (molecular weight 351) from the elemental analysis and mass spectrum. The antibiotic possesses antifungal activity and potent inhibitory activity against various RNA and DNA viruses.

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Year:  1981        PMID： 7319904     DOI： 10.7164/antibiotics.34.1408

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  8 in total

1.  β-Hydroxy-tetrahydroquinolines from Quinolines Using Chloroborane: Synthesis of the Peptidomimetic FISLE-412.

Authors:  Ahmad S Altiti; Kai Fan Cheng; Mingzhu He; Yousef Al-Abed
Journal:  Chemistry       Date:  2017-07-26       Impact factor: 5.236

2.  Studies on novel HIF activators, A-503451s.I. Producing organism, fermentation, isolation and structural elucidation.

Authors:  Yuki Hirota-Takahata; Hideki Kobayashi; Masaaki Kizuka; Takao Ohyama; Michiko Kitamura-Miyazaki; Yasuhiro Suzuki; Mie Fujiwara; Mutsuo Nakajima; Osamu Ando
Journal:  J Antibiot (Tokyo)       Date:  2016-03-09       Impact factor: 2.649

Review 3.  Philosophy of new drug discovery.

Authors:  S Omura
Journal:  Microbiol Rev       Date:  1986-09

4.  Catalytic Aminohalogenation of Alkenes and Alkynes.

Authors:  Sherry R Chemler; Michael T Bovino
Journal:  ACS Catal       Date:  2013-06-07       Impact factor: 13.084

Review 5.  Bacterial terpenome.

Authors:  Jeffrey D Rudolf; Tyler A Alsup; Baofu Xu; Zining Li
Journal:  Nat Prod Rep       Date:  2021-05-26       Impact factor: 15.111

Review 6.  Synthetic and medicinal perspective of quinolines as antiviral agents.

Authors:  Ramandeep Kaur; Kapil Kumar
Journal:  Eur J Med Chem       Date:  2021-01-24       Impact factor: 6.514

7.  Asymmetric Synthesis of Heterocyclic Chloroamines and Aziridines by Enantioselective Protonation of Catalytically Generated Enamines.

Authors:  Liam A McLean; Matthew W Ashford; James W B Fyfe; Alexandra M Z Slawin; Andrew G Leach; Allan J B Watson
Journal:  Chemistry       Date:  2022-02-23       Impact factor: 5.020

8.  A Multistage In Silico Study of Natural Potential Inhibitors Targeting SARS-CoV-2 Main Protease.

Authors:  Eslam B Elkaeed; Ibrahim H Eissa; Hazem Elkady; Ahmed Abdelalim; Ahmad M Alqaisi; Aisha A Alsfouk; Alaa Elwan; Ahmed M Metwaly
Journal:  Int J Mol Sci       Date:  2022-07-29       Impact factor: 6.208
  8 in total

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