Literature DB >> 3534537

Philosophy of new drug discovery.

S Omura.   

Abstract

Mesh:

Substances:

Year:  1986        PMID: 3534537      PMCID: PMC373071          DOI: 10.1128/mr.50.3.259-279.1986

Source DB:  PubMed          Journal:  Microbiol Rev        ISSN: 0146-0749


× No keyword cloud information.
  89 in total

Review 1.  Ivermectin: a review of efficacy and safety.

Authors:  W C Campbell; G W Benz
Journal:  J Vet Pharmacol Ther       Date:  1984-03       Impact factor: 1.786

2.  Cerulenin resistance in a cerulenin-producing fungus. III. Studies on active-site peptides of fatty acid synthetase from Cephalosporium caerulens.

Authors:  H Tomoda; A Kawaguchi; T Yasuhara; T Nakajima; S Omura; S Okuda
Journal:  J Biochem       Date:  1984-06       Impact factor: 3.387

3.  The structure of phosalacine, a new herbicidal antibiotic containing phosphinothricin.

Authors:  S Omura; K Hinotozawa; N Imamura; M Murata
Journal:  J Antibiot (Tokyo)       Date:  1984-08       Impact factor: 2.649

4.  Repression of beta-lactam production in Cephalosporium acremonium by nitrogen sources.

Authors:  Y Q Shen; J Heim; N A Solomon; S Wolfe; A L Demain
Journal:  J Antibiot (Tokyo)       Date:  1984-05       Impact factor: 2.649

5.  Phosalacine, a new herbicidal antibiotic containing phosphinothricin. Fermentation, isolation, biological activity and mechanism of action.

Authors:  S Omura; M Murata; H Hanaki; K Hinotozawa; R Oiwa; H Tanaka
Journal:  J Antibiot (Tokyo)       Date:  1984-08       Impact factor: 2.649

6.  Effect of ammonium ion, inorganic phosphate and amino acids on the biosynthesis of protylonolide, a precursor of tylosin aglycone.

Authors:  S Omura; Y Tanaka; H Mamada; R Masuma
Journal:  J Antibiot (Tokyo)       Date:  1984-05       Impact factor: 2.649

7.  Takaokamycin, a new peptide antibiotic produced by Streptomyces sp.

Authors:  S Omura; H Mamada; N J Wang; N Imamura; R Oiwa; Y Iwai; N Muto
Journal:  J Antibiot (Tokyo)       Date:  1984-07       Impact factor: 2.649

8.  Chemical modification and antitumor activity of herbimycin A. 8,9-Epoxide, 7,9-cyclic carbamate, and 17 or 19-amino derivatives.

Authors:  S Omura; K Miyano; A Nakagawa; H Sano; K Komiyama; I Umezawa; K Shibata; S Satsumabayashi
Journal:  J Antibiot (Tokyo)       Date:  1984-10       Impact factor: 2.649

9.  Oxetin, a new antimetabolite from an actinomycete. Fermentation, isolation, structure and biological activity.

Authors:  S Omura; M Murata; N Imamura; Y Iwai; H Tanaka; A Furusaki; H Matsumoto
Journal:  J Antibiot (Tokyo)       Date:  1984-11       Impact factor: 2.649

10.  Gastrointestinal motor-stimulating activity of macrolide antibiotics and analysis of their side effects on the canine gut.

Authors:  Z Itoh; T Suzuki; M Nakaya; M Inoue; S Mitsuhashi
Journal:  Antimicrob Agents Chemother       Date:  1984-12       Impact factor: 5.191

View more
  12 in total

Review 1.  Thom Award Lecture. Trends in the search for bioactive microbial metabolites.

Authors:  S Omura
Journal:  J Ind Microbiol       Date:  1992-09

2.  Screening for a new generation of anthelminthic compounds. In vitro selection of the nematode Caenorhabditis elegans for ivermectin resistance.

Authors:  J Novák; Z Vanĕk
Journal:  Folia Microbiol (Praha)       Date:  1992       Impact factor: 2.099

Review 3.  Biotechnology and biosynthesis of quinones.

Authors:  A J Van den Berg
Journal:  Pharm Weekbl Sci       Date:  1991-04-26

4.  Rapid analysis of antibiotic-containing mixtures from fermentation broths by using liquid chromatography-electrospray ionization-mass spectrometry and matrix-assisted laser desorption ionization-time-of-flight-mass spectrometry.

Authors:  B L Ackermann; B T Regg; L Colombo; S Stella; J E Coutant
Journal:  J Am Soc Mass Spectrom       Date:  1996-12       Impact factor: 3.109

5.  A rapid method for screening large numbers of environmental microorganisms for antiviral activity.

Authors:  C Maullu; G Lampis; D Deidda; S Petruzzelli; R Pompei
Journal:  Appl Environ Microbiol       Date:  1998-03       Impact factor: 4.792

Review 6.  Flow cytometry and cell sorting of heterogeneous microbial populations: the importance of single-cell analyses.

Authors:  H M Davey; D B Kell
Journal:  Microbiol Rev       Date:  1996-12

Review 7.  Streptomyces cloning: useful recombinant DNA systems and a summation of cloned genes.

Authors:  P K Tomich
Journal:  Antimicrob Agents Chemother       Date:  1988-10       Impact factor: 5.191

8.  Bioactive compounds from marine actinomycetes.

Authors:  Renu Solanki; Monisha Khanna; Rup Lal
Journal:  Indian J Microbiol       Date:  2009-01-08       Impact factor: 2.461

9.  Molecular screening of Streptomyces isolates for antifungal activity and family 19 chitinase enzymes.

Authors:  Youssuf Gherbawy; Hesham Elhariry; Abdulla Altalhi; Bahig El-Deeb; Ghada Khiralla
Journal:  J Microbiol       Date:  2012-06-30       Impact factor: 3.422

10.  Isolation and characterization of a cytotoxic metabolite of Talaromyces bacillosporus.

Authors:  K Ishii; T Itoh; K Kobayashi; Y Horie; Y Ueno
Journal:  Appl Environ Microbiol       Date:  1995-03       Impact factor: 4.792

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.