Literature DB >> 7209515

Vasopressin analogs that antagonize antidiuretic responses by rats to the antidiuretic hormone.

W H Sawyer, P K Pang, J Seto, M McEnroe, B Lammek, M Manning.   

Abstract

Four new synthetic analogs of vasopressin (antidiuretic hormone) can antagonize the antidiuretic response to intravenous vasopressin in anesthetized, water-loaded rats. They also cause a diuresis resembling that of diabetes insipidus when given intraperitoneally to conscious rats. Such antagonists may prove to be useful both pharmacologically and therapeutically.

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Year:  1981        PMID： 7209515     DOI： 10.1126/science.7209515

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  11 in total

1.  Sustained aquaretic effect of the V2-AVP receptor antagonist, RWJ-351647, in cirrhotic rats with ascites and water retention.

Authors:  Josefa Ros; Guillermo Fernández-Varo; Javier Muñoz-Luque; Vicente Arroyo; Juan Rodés; Joseph W Gunnet; Keith T Demarest; Wladimiro Jiménez
Journal:  Br J Pharmacol       Date:  2005-11       Impact factor: 8.739

Review 2.  Emerging approaches in the molecular design of receptor-selective peptide ligands: conformational, topographical and dynamic considerations.

Authors:  V J Hruby; F al-Obeidi; W Kazmierski
Journal:  Biochem J       Date:  1990-06-01       Impact factor: 3.857

3.  Release of vasopressin and oxytocin by excitatory amino acid agonists and the effect of antagonists on release by muscarine and hypertonic saline, in the rat in vivo.

Authors:  G W Bisset; K M Fairhall
Journal:  Br J Pharmacol       Date:  1996-01       Impact factor: 8.739

Review 4.  Arginine vasopressin (AVP) and treatment with arginine vasopressin receptor antagonists (vaptans) in congestive heart failure, liver cirrhosis and syndrome of inappropriate antidiuretic hormone secretion (SIADH).

Authors:  Natig Gassanov; Nasser Semmo; Mariam Semmo; Amir M Nia; Uwe Fuhr; Fikret Er
Journal:  Eur J Clin Pharmacol       Date:  2011-02-17       Impact factor: 2.953

5.  [Cardiovascular effect of the antidiuretic hormone arginine vasopressin].

Authors:  W Rascher
Journal:  Klin Wochenschr       Date:  1985-10-01

6.  A cholinergic link in the reflex release of vasopressin by hypotension in the rat.

Authors:  G W Bisset; H S Chowdrey
Journal:  J Physiol       Date:  1984-09       Impact factor: 5.182

7.  Central inhibition by gamma-aminobutyric acid and muscimol of the release of vasopressin and oxytocin by an osmotic stimulus in the rat.

Authors:  G W Bisset; H S Chowdrey; K M Fairhall; L K Gunn
Journal:  Br J Pharmacol       Date:  1990-03       Impact factor: 8.739

Review 8.  Cyclic Peptides that Govern Signal Transduction Pathways: From Prokaryotes to Multi-Cellular Organisms.

Authors:  Ryan W Mull; Anthony Harrington; Lucia A Sanchez; Yftah Tal-Gan
Journal:  Curr Top Med Chem       Date:  2018       Impact factor: 3.295

9.  Effects of vasopressin antagonist on vasopressin binding, adenylate cyclase activation, and water flux.

Authors:  J K Kim; M A Dillingham; S N Summer; S Ishikawa; R J Anderson; R W Schrier
Journal:  J Clin Invest       Date:  1985-10       Impact factor: 14.808

10.  Immunohistochemical localization of V2 vasopressin receptor along the nephron and functional role of luminal V2 receptor in terminal inner medullary collecting ducts.

Authors:  H Nonoguchi; A Owada; N Kobayashi; M Takayama; Y Terada; J Koike; K Ujiie; F Marumo; T Sakai; K Tomita
Journal:  J Clin Invest       Date:  1995-10       Impact factor: 14.808
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